Cargando…

Candesartan Normalizes Changes in Retinal Blood Flow and p22phox in the Diabetic Rat Retina

Angiotensin II has been implicated in the progression of diabetic retinopathy, which is characterized by altered microvasculature, oxidative stress, and neuronal dysfunction. The signaling induced by angiotensin II can occur not only via receptor-mediated calcium release that causes vascular constri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eshaq, Randa S., Watts, Megan N., Carter, Patsy R., Leskova, Wendy, Aw, Tak Yee, Alexander, Jonathan Steven, Harris, Norman R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830460/ https://www.ncbi.nlm.nih.gov/pubmed/35366272 http://dx.doi.org/10.3390/pathophysiology28010008

Ejemplares similares

The Endothelial Glycocalyx and Retinal Hemodynamics
por: Kaur, Gaganpreet, et al.
Publicado: (2022)

Loss of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) in the Diabetic Retina: Role of Matrix Metalloproteinases
por: Eshaq, Randa S., et al.
Publicado: (2019)

Altered Retinal Hemodynamics and Mean Circulation Time in Spontaneously Hypertensive Rats
por: Leskova, Wendy, et al.
Publicado: (2020)

Pioglitazone Inhibits the Expressions of p22(phox) and p47(phox) in Rat Mesangial Cells In Vitro
por: Wang, Shan, et al.
Publicado: (2014)

Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity
por: Zang, Jie, et al.
Publicado: (2023)

ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytes
por: Tlili, Asma, et al.
Publicado: (2023)

New NADPH Oxidase 2 Inhibitors Display Potent Activity against Oxidative Stress by Targeting p22(phox)-p47(phox) Interactions
por: Treuer, Adriana V., et al.
Publicado: (2023)

Candesartan in heart failure
por: Ripley, Toni L, et al.
Publicado: (2006)

156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox
Publicado: (1994)

Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function
por: Miller, Antonia G., et al.
Publicado: (2010)

p22phox confers resistance to cisplatin, by blocking its entry into the nucleus
por: Hung, Chih-Chang, et al.
Publicado: (2015)

The correlation of p22(phox) and chemosensitivity in EGFR-TKI resistant lung adenocarcinoma
por: Kobayashi, Masayuki, et al.
Publicado: (2019)

Cost Effectiveness Analysis of Candesartan Therapy in Comparison to Candesartan-Amlodipine Therapy on Hypertensive Outpatients
por: Baroroh, Faridah, et al.
Publicado: (2019)

Ethers and esters derived from apocynin avoid the interaction between p47phox and p22phox subunits of NADPH oxidase: evaluation in vitro and in silico
por: Macías-Pérez, Martha Edith, et al.
Publicado: (2013)

Inhibition of p22(phox) Suppresses Epithelial Ovarian Cancer Cell Proliferation and Tumorigenesis
por: Li, Qi, et al.
Publicado: (2021)

Oxygen delivery, consumption, and conversion to reactive oxygen species in experimental models of diabetic retinopathy
por: Eshaq, Randa S., et al.
Publicado: (2014)

Smooth Muscle Specific Overexpression of p22(phox) Potentiates Carotid Artery Wall Thickening in Response to Injury
por: Manogue, Michael R., et al.
Publicado: (2015)

Regulation of NOXO1 Activity through Reversible Interactions with p22(phox) and NOXA1
por: Dutta, Sujit, et al.
Publicado: (2010)

Libyan Boy with Autosomal Recessive Trait (P22-phox Defect) of Chronic Granulomatous Disease
por: Al-Bousafy, Ahmed, et al.
Publicado: (2006)

Candesartan—the next anti-amyloid drug?
por: Yasar, Sevil
Publicado: (2022)

Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22(phox) by thiol modification
por: Miyano, Kei, et al.
Publicado: (2022)

Exercise Training Attenuates Upregulation of p47(phox) and p67(phox) in Hearts of Diabetic Rats
por: Sharma, Neeru M., et al.
Publicado: (2016)

Candesartan cilexetil in the treatment of chronic heart failure
por: Baguet, Jean-Philippe, et al.
Publicado: (2009)

Cardio classics revisited – focus on the role of candesartan
por: De Rosa, Maria Leonarda
Publicado: (2010)

Preparation of Candesartan and Atorvastatin Nanoparticles by Solvent Evaporation (†)
por: Vaculikova, Eliska, et al.
Publicado: (2012)

Candesartan induces tumor vascular normalization to improve the efficacy of radiotherapy in the therapeutic window
por: Zhu, Fei, et al.
Publicado: (2022)

Long-term outcome of patients with p22(phox)-deficient chronic granulomatous disease on Jeju Island, Korea
por: Kang, Hyun Sik, et al.
Publicado: (2015)

NADPH Oxidase p22(phox) C242T Polymorphism and Ischemic Cerebrovascular Disease: An Updated Meta-Analysis
por: Li, Pingping, et al.
Publicado: (2015)

Mito-TIPTP Increases Mitochondrial Function by Repressing the Rubicon-p22phox Interaction in Colitis-Induced Mice
por: Kim, Jae-Sung, et al.
Publicado: (2021)

p47phox contributes to albuminuria and kidney fibrosis in mice
por: Wang, Hongtao, et al.
Publicado: (2015)

PhoX: An IMAC-Enrichable Cross-Linking Reagent
por: Steigenberger, Barbara, et al.
Publicado: (2019)

ROS production and mitochondrial dysfunction driven by PU.1-regulated NOX4-p22(phox) activation in Aβ-induced retinal pigment epithelial cell injury
por: Sun, Junran, et al.
Publicado: (2020)

Effects of adriamycin and candesartan on the collagen and elastin of the aorta in rats
por: Uhm, Jae-Sun, et al.
Publicado: (2014)

Candesartan could ameliorate the COVID-19 cytokine storm
por: Elkahloun, Abdel G., et al.
Publicado: (2020)

Candesartan cilexetil: COVID-19 pneumonia: case report
Publicado: (2020)

Repurposing Candesartan Cilexetil as Antibacterial Agent for MRSA Infection
por: Xu, Lanlan, et al.
Publicado: (2021)

Population Pharmacokinetics of Candesartan in Patients with Chronic Heart Failure
por: Kassem, Imad, et al.
Publicado: (2020)

The C242T polymorphism of the p22-phox gene (CYBA) is associated with higher left ventricular mass in Brazilian hypertensive patients
por: Schreiber, Roberto, et al.
Publicado: (2011)

Candesartan cilexetil/hydrochlorothiazide combination treatment versus high-dose candesartan cilexetil monotherapy in patients with mild to moderate cardiovascular risk (CHILI Triple T)
por: Bönner, Gerd, et al.
Publicado: (2011)

Proton Conduction through gp91(phox)
por: Henderson, Lydia M., et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_hf89lir7je80veo86fns2mqjj2