Using Polyacrylamide Hydrogels to Model Physiological Aortic Stiffness Reveals that Microtubules Are Critical Regulators of Isolated Smooth Muscle Cell Morphology and Contractility

Vascular smooth muscle cells (VSMCs) are the predominant cell type in the medial layer of the aortic wall and normally exist in a quiescent, contractile phenotype where actomyosin-derived contractile forces maintain vascular tone. However, VSMCs are not terminally differentiated and can dedifferenti...

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Detalles Bibliográficos
Autores principales: Ahmed, Sultan, Johnson, Robert. T., Solanki, Reesha, Afewerki, Teclino, Wostear, Finn, Warren, Derek. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830533/
https://www.ncbi.nlm.nih.gov/pubmed/35153800
http://dx.doi.org/10.3389/fphar.2022.836710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830533/
https://www.ncbi.nlm.nih.gov/pubmed/35153800
http://dx.doi.org/10.3389/fphar.2022.836710

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