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The clinical conundrum of a catecholamine secreting giant adrenal myelolipoma

Adrenal myelolipomas are uncommon tumours of unknown aetiology. They arise from the adrenal cortex and comprise lipomatous and myeloid elements. They are considered to be functionally inert, and metabolic evaluation is not mandatory for them. Adrenal myelolipomas can rarely be functionally active, a...

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Detalles Bibliográficos
Autores principales: Jindal, Tarun, Mukherjee, Satyadip, Koju, Rajan, Giri, Sandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830559/
https://www.ncbi.nlm.nih.gov/pubmed/34259211
http://dx.doi.org/10.4103/jmas.JMAS_14_21
Descripción
Sumario:Adrenal myelolipomas are uncommon tumours of unknown aetiology. They arise from the adrenal cortex and comprise lipomatous and myeloid elements. They are considered to be functionally inert, and metabolic evaluation is not mandatory for them. Adrenal myelolipomas can rarely be functionally active, and patients may present with hypertension, electrolyte imbalance or features of Cushing's syndrome. The association of these tumours with catecholamine secretion is exceptionally rare. We describe a case of a functional adrenal myelolipoma associated with catecholamine secretion in a 55-year-old female patient with a history of hypertension. The surgical excision of the mass resulted in normalisation of the urinary catecholamine levels and resolution of the hypertension.