Cargando…

Circadian control of heparan sulfate levels times phagocytosis of amyloid beta aggregates

Alzheimer’s Disease (AD) is a neuroinflammatory disease characterized partly by the inability to clear, and subsequent build-up, of amyloid-beta (Aβ). AD has a bi-directional relationship with circadian disruption (CD) with sleep disturbances starting years before disease onset. However, the molecul...

Descripción completa

Detalles Bibliográficos
Autores principales: Clark, Gretchen T., Yu, Yanlei, Urban, Cooper A., Fu, Guo, Wang, Chunyu, Zhang, Fuming, Linhardt, Robert J., Hurley, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830681/
https://www.ncbi.nlm.nih.gov/pubmed/35143487
http://dx.doi.org/10.1371/journal.pgen.1009994