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Circadian control of heparan sulfate levels times phagocytosis of amyloid beta aggregates
Alzheimer’s Disease (AD) is a neuroinflammatory disease characterized partly by the inability to clear, and subsequent build-up, of amyloid-beta (Aβ). AD has a bi-directional relationship with circadian disruption (CD) with sleep disturbances starting years before disease onset. However, the molecul...
Autores principales: | Clark, Gretchen T., Yu, Yanlei, Urban, Cooper A., Fu, Guo, Wang, Chunyu, Zhang, Fuming, Linhardt, Robert J., Hurley, Jennifer M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830681/ https://www.ncbi.nlm.nih.gov/pubmed/35143487 http://dx.doi.org/10.1371/journal.pgen.1009994 |
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