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Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types

Existing studies of chromatin conformation have primarily focused on potential enhancers interacting with gene promoters. By contrast, the interactivity of promoters per se, while equally critical to understanding transcriptional control, has been largely unexplored, particularly in a cell type-spec...

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Detalles Bibliográficos
Autores principales: Wen, Jia, Lagler, Taylor M., Sun, Quan, Yang, Yuchen, Chen, Jiawen, Harigaya, Yuriko, Sankaran, Vijay G., Hu, Ming, Reiner, Alexander P., Raffield, Laura M., Li, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830683/
https://www.ncbi.nlm.nih.gov/pubmed/35100265
http://dx.doi.org/10.1371/journal.pgen.1009984