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Predicted impact of the viral mutational landscape on the cytotoxic response against SARS-CoV-2

The massive assessment of immune evasion due to viral mutations that increase COVID-19 susceptibility can be computationally facilitated. The adaptive cytotoxic T response is critical during primary infection and the generation of long-term protection. Here, potential HLA class I epitopes in the SAR...

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Detalles Bibliográficos
Autores principales: Foix, Anna, López, Daniel, Díez-Fuertes, Francisco, McConnell, Michael J., Martín-Galiano, Antonio J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830725/
https://www.ncbi.nlm.nih.gov/pubmed/35143484
http://dx.doi.org/10.1371/journal.pcbi.1009726