Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing

Mammalian hearing involves the mechanoelectrical transduction (MET) of sound-induced fluid waves in the cochlea. Essential to this process are the specialised sensory cochlear cells, the inner (IHCs) and outer hair cells (OHCs). While genetic hearing loss is highly heterogeneous, understanding the r...

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Detalles Bibliográficos
Autores principales: Newton, Sherylanne, Kong, Fanbo, Carlton, Adam J., Aguilar, Carlos, Parker, Andrew, Codner, Gemma F., Teboul, Lydia, Wells, Sara, Brown, Steve D. M., Marcotti, Walter, Bowl, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830789/
https://www.ncbi.nlm.nih.gov/pubmed/35100259
http://dx.doi.org/10.1371/journal.pgen.1009937

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