Meta-imputation of transcriptome from genotypes across multiple datasets by leveraging publicly available summary-level data

Transcriptome wide association studies (TWAS) can be used as a powerful method to identify and interpret the underlying biological mechanisms behind GWAS by mapping gene expression levels with phenotypes. In TWAS, gene expression is often imputed from individual-level genotypes of regulatory variant...

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Detalles Bibliográficos
Autores principales: Liu, Andrew E., Kang, Hyun Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830793/
https://www.ncbi.nlm.nih.gov/pubmed/35100255
http://dx.doi.org/10.1371/journal.pgen.1009571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830793/
https://www.ncbi.nlm.nih.gov/pubmed/35100255
http://dx.doi.org/10.1371/journal.pgen.1009571

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