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COVID-19 and the cardiovascular system: an update
As COVID-19 continues to cause an increasing number of deaths worldwide, it is important that providers stay abreast with new research related to the pathophysiology of COVID-19 disease presentation states and clinical management. It is now well recognized that COVID-19 affects extrapulmonary organs...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Southern Society for Clinical Investigation. Published by Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830924/ https://www.ncbi.nlm.nih.gov/pubmed/35151635 http://dx.doi.org/10.1016/j.amjms.2022.01.022 |
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author | Salabei, Joshua K. Asnake, Zekarias T. Ismail, Zeeshan H. Charles, Kipson Stanger, Gregory-Thomas Abdullahi, Abdullahi H. Abraham, Andrew T. Okonoboh, Peters |
author_facet | Salabei, Joshua K. Asnake, Zekarias T. Ismail, Zeeshan H. Charles, Kipson Stanger, Gregory-Thomas Abdullahi, Abdullahi H. Abraham, Andrew T. Okonoboh, Peters |
author_sort | Salabei, Joshua K. |
collection | PubMed |
description | As COVID-19 continues to cause an increasing number of deaths worldwide, it is important that providers stay abreast with new research related to the pathophysiology of COVID-19 disease presentation states and clinical management. It is now well recognized that COVID-19 affects extrapulmonary organs, particularly the cardiovascular system. For example, cardiogenic shock has been increasingly observed in patients with COVID-19, owing to the various mechanisms involved and the affinity of the SARS-CoV-2 virus to cells comprising the cardiovascular system. In this review, we have briefly discussed the link between the cardiovascular system and COVID-19 infection, focusing on underlying mechanisms including but not limited to cytokine storm, direct virus-induced myocarditis, and ST-elevation myocardial infarction leading to cardiogenic shock. We have highlighted the cardiovascular risk factors associated with disease prognostication in COVID-19 patients. We have also briefly discussed vasopressors and inotropes used for treating shock and presented their mechanism of action, contraindications, and side effects in the hopes of providing a quick reference to help the provider optimize management of COVID-19 patients presenting with cardiovascular complications such as shock. |
format | Online Article Text |
id | pubmed-8830924 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Southern Society for Clinical Investigation. Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-88309242022-02-11 COVID-19 and the cardiovascular system: an update Salabei, Joshua K. Asnake, Zekarias T. Ismail, Zeeshan H. Charles, Kipson Stanger, Gregory-Thomas Abdullahi, Abdullahi H. Abraham, Andrew T. Okonoboh, Peters Am J Med Sci Review Article As COVID-19 continues to cause an increasing number of deaths worldwide, it is important that providers stay abreast with new research related to the pathophysiology of COVID-19 disease presentation states and clinical management. It is now well recognized that COVID-19 affects extrapulmonary organs, particularly the cardiovascular system. For example, cardiogenic shock has been increasingly observed in patients with COVID-19, owing to the various mechanisms involved and the affinity of the SARS-CoV-2 virus to cells comprising the cardiovascular system. In this review, we have briefly discussed the link between the cardiovascular system and COVID-19 infection, focusing on underlying mechanisms including but not limited to cytokine storm, direct virus-induced myocarditis, and ST-elevation myocardial infarction leading to cardiogenic shock. We have highlighted the cardiovascular risk factors associated with disease prognostication in COVID-19 patients. We have also briefly discussed vasopressors and inotropes used for treating shock and presented their mechanism of action, contraindications, and side effects in the hopes of providing a quick reference to help the provider optimize management of COVID-19 patients presenting with cardiovascular complications such as shock. Southern Society for Clinical Investigation. Published by Elsevier Inc. 2022-08 2022-02-11 /pmc/articles/PMC8830924/ /pubmed/35151635 http://dx.doi.org/10.1016/j.amjms.2022.01.022 Text en © 2022 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Review Article Salabei, Joshua K. Asnake, Zekarias T. Ismail, Zeeshan H. Charles, Kipson Stanger, Gregory-Thomas Abdullahi, Abdullahi H. Abraham, Andrew T. Okonoboh, Peters COVID-19 and the cardiovascular system: an update |
title | COVID-19 and the cardiovascular system: an update |
title_full | COVID-19 and the cardiovascular system: an update |
title_fullStr | COVID-19 and the cardiovascular system: an update |
title_full_unstemmed | COVID-19 and the cardiovascular system: an update |
title_short | COVID-19 and the cardiovascular system: an update |
title_sort | covid-19 and the cardiovascular system: an update |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830924/ https://www.ncbi.nlm.nih.gov/pubmed/35151635 http://dx.doi.org/10.1016/j.amjms.2022.01.022 |
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