Inhaled heparin polysaccharide nanodecoy against SARS-CoV-2 and variants

The heparin polysaccharide nanoparticles block the interaction between heparan sulfate/S protein and inhibit the infection of both wild-type SARS-CoV-2 pseudovirus and the mutated strains through pulmonary delivery. [Figure: see text]

Detalles Bibliográficos
Autores principales: Tu, Bin, Wang, Huiyuan, An, Xinran, Qu, Jingkun, Li, Qianqian, Gao, Yanrong, Shi, Mingjie, Qiu, Hong, Huang, Yongzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830937/
https://www.ncbi.nlm.nih.gov/pubmed/35169535
http://dx.doi.org/10.1016/j.apsb.2022.01.019
Descripción
Sumario:The heparin polysaccharide nanoparticles block the interaction between heparan sulfate/S protein and inhibit the infection of both wild-type SARS-CoV-2 pseudovirus and the mutated strains through pulmonary delivery. [Figure: see text]

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