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High levels of monocytic myeloid-derived suppressor cells are associated with favorable outcome in patients with pneumonia and sepsis with multi-organ failure

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells with immunosuppressive functions sub-classified into monocytic and polymorphonuclear MDSCs (M-MDSCs and PMN-MDSCs). Clinical studies reported increased levels of MDSCs that were associated with poor outcome in sepsis pat...

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Detalles Bibliográficos
Autores principales: Schrijver, Irene T., Karakike, Eleni, Théroude, Charlotte, Baumgartner, Pétra, Harari, Alexandre, Giamarellos-Bourboulis, Evangelos J., Calandra, Thierry, Roger, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831012/
https://www.ncbi.nlm.nih.gov/pubmed/35146585
http://dx.doi.org/10.1186/s40635-022-00431-0