Cargando…

Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation

Hashimoto's thyroiditis is the most common thyroid disorder in the United States. Hashimoto encephalopathy is a rare presentation of Hashimoto's thyroiditis that is frequently misdiagnosed. We present the case of a 71-year-old female who had normal mental status at baseline. She presented...

Descripción completa

Detalles Bibliográficos
Autores principales: Khatib, Sohaib, Jaber, Fouad, Elsayed, Marwa, Shatla, Islam M, Hamarshi, Majdi S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831211/
https://www.ncbi.nlm.nih.gov/pubmed/35165583
http://dx.doi.org/10.7759/cureus.21130
_version_ 1784648455283539968
author Khatib, Sohaib
Jaber, Fouad
Elsayed, Marwa
Shatla, Islam M
Hamarshi, Majdi S
author_facet Khatib, Sohaib
Jaber, Fouad
Elsayed, Marwa
Shatla, Islam M
Hamarshi, Majdi S
author_sort Khatib, Sohaib
collection PubMed
description Hashimoto's thyroiditis is the most common thyroid disorder in the United States. Hashimoto encephalopathy is a rare presentation of Hashimoto's thyroiditis that is frequently misdiagnosed. We present the case of a 71-year-old female who had normal mental status at baseline. She presented with acute alteration in mental status. Further evaluation with brain MRI showed a hyperintense signal in the bilateral centrum. Spinal fluid analysis revealed elevated protein. Thyroid peroxidase (TPO) antibody was elevated at 59.7 and TSH was elevated at 4.9. Her mental status improved dramatically after treatment with steroids and levothyroxine. This diagnosis should be suspected when the patient develops acute encephalopathy with positive serum thyroid antibody settings with a complete return to normal mental status after treatment with steroids.
format Online
Article
Text
id pubmed-8831211
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-88312112022-02-13 Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation Khatib, Sohaib Jaber, Fouad Elsayed, Marwa Shatla, Islam M Hamarshi, Majdi S Cureus Endocrinology/Diabetes/Metabolism Hashimoto's thyroiditis is the most common thyroid disorder in the United States. Hashimoto encephalopathy is a rare presentation of Hashimoto's thyroiditis that is frequently misdiagnosed. We present the case of a 71-year-old female who had normal mental status at baseline. She presented with acute alteration in mental status. Further evaluation with brain MRI showed a hyperintense signal in the bilateral centrum. Spinal fluid analysis revealed elevated protein. Thyroid peroxidase (TPO) antibody was elevated at 59.7 and TSH was elevated at 4.9. Her mental status improved dramatically after treatment with steroids and levothyroxine. This diagnosis should be suspected when the patient develops acute encephalopathy with positive serum thyroid antibody settings with a complete return to normal mental status after treatment with steroids. Cureus 2022-01-11 /pmc/articles/PMC8831211/ /pubmed/35165583 http://dx.doi.org/10.7759/cureus.21130 Text en Copyright © 2022, Khatib et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Khatib, Sohaib
Jaber, Fouad
Elsayed, Marwa
Shatla, Islam M
Hamarshi, Majdi S
Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation
title Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation
title_full Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation
title_fullStr Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation
title_full_unstemmed Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation
title_short Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation
title_sort hashimoto’s thyroiditis presents as an acute encephalopathy: a case report of unusual presentation
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831211/
https://www.ncbi.nlm.nih.gov/pubmed/35165583
http://dx.doi.org/10.7759/cureus.21130
work_keys_str_mv AT khatibsohaib hashimotosthyroiditispresentsasanacuteencephalopathyacasereportofunusualpresentation
AT jaberfouad hashimotosthyroiditispresentsasanacuteencephalopathyacasereportofunusualpresentation
AT elsayedmarwa hashimotosthyroiditispresentsasanacuteencephalopathyacasereportofunusualpresentation
AT shatlaislamm hashimotosthyroiditispresentsasanacuteencephalopathyacasereportofunusualpresentation
AT hamarshimajdis hashimotosthyroiditispresentsasanacuteencephalopathyacasereportofunusualpresentation