Cargando…
Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation
Hashimoto's thyroiditis is the most common thyroid disorder in the United States. Hashimoto encephalopathy is a rare presentation of Hashimoto's thyroiditis that is frequently misdiagnosed. We present the case of a 71-year-old female who had normal mental status at baseline. She presented...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831211/ https://www.ncbi.nlm.nih.gov/pubmed/35165583 http://dx.doi.org/10.7759/cureus.21130 |
_version_ | 1784648455283539968 |
---|---|
author | Khatib, Sohaib Jaber, Fouad Elsayed, Marwa Shatla, Islam M Hamarshi, Majdi S |
author_facet | Khatib, Sohaib Jaber, Fouad Elsayed, Marwa Shatla, Islam M Hamarshi, Majdi S |
author_sort | Khatib, Sohaib |
collection | PubMed |
description | Hashimoto's thyroiditis is the most common thyroid disorder in the United States. Hashimoto encephalopathy is a rare presentation of Hashimoto's thyroiditis that is frequently misdiagnosed. We present the case of a 71-year-old female who had normal mental status at baseline. She presented with acute alteration in mental status. Further evaluation with brain MRI showed a hyperintense signal in the bilateral centrum. Spinal fluid analysis revealed elevated protein. Thyroid peroxidase (TPO) antibody was elevated at 59.7 and TSH was elevated at 4.9. Her mental status improved dramatically after treatment with steroids and levothyroxine. This diagnosis should be suspected when the patient develops acute encephalopathy with positive serum thyroid antibody settings with a complete return to normal mental status after treatment with steroids. |
format | Online Article Text |
id | pubmed-8831211 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-88312112022-02-13 Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation Khatib, Sohaib Jaber, Fouad Elsayed, Marwa Shatla, Islam M Hamarshi, Majdi S Cureus Endocrinology/Diabetes/Metabolism Hashimoto's thyroiditis is the most common thyroid disorder in the United States. Hashimoto encephalopathy is a rare presentation of Hashimoto's thyroiditis that is frequently misdiagnosed. We present the case of a 71-year-old female who had normal mental status at baseline. She presented with acute alteration in mental status. Further evaluation with brain MRI showed a hyperintense signal in the bilateral centrum. Spinal fluid analysis revealed elevated protein. Thyroid peroxidase (TPO) antibody was elevated at 59.7 and TSH was elevated at 4.9. Her mental status improved dramatically after treatment with steroids and levothyroxine. This diagnosis should be suspected when the patient develops acute encephalopathy with positive serum thyroid antibody settings with a complete return to normal mental status after treatment with steroids. Cureus 2022-01-11 /pmc/articles/PMC8831211/ /pubmed/35165583 http://dx.doi.org/10.7759/cureus.21130 Text en Copyright © 2022, Khatib et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Endocrinology/Diabetes/Metabolism Khatib, Sohaib Jaber, Fouad Elsayed, Marwa Shatla, Islam M Hamarshi, Majdi S Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation |
title | Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation |
title_full | Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation |
title_fullStr | Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation |
title_full_unstemmed | Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation |
title_short | Hashimoto’s Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation |
title_sort | hashimoto’s thyroiditis presents as an acute encephalopathy: a case report of unusual presentation |
topic | Endocrinology/Diabetes/Metabolism |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831211/ https://www.ncbi.nlm.nih.gov/pubmed/35165583 http://dx.doi.org/10.7759/cureus.21130 |
work_keys_str_mv | AT khatibsohaib hashimotosthyroiditispresentsasanacuteencephalopathyacasereportofunusualpresentation AT jaberfouad hashimotosthyroiditispresentsasanacuteencephalopathyacasereportofunusualpresentation AT elsayedmarwa hashimotosthyroiditispresentsasanacuteencephalopathyacasereportofunusualpresentation AT shatlaislamm hashimotosthyroiditispresentsasanacuteencephalopathyacasereportofunusualpresentation AT hamarshimajdis hashimotosthyroiditispresentsasanacuteencephalopathyacasereportofunusualpresentation |