Insights Into the Emergence of Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria (PNH) is a disease as simple as it is complex. PNH patients develop somatic loss-of-function mutations in phosphatidylinositol N-acetylglucosaminyltransferase subunit A gene (PIGA), required for the biosynthesis of glycosylphosphatidylinositol (GPI) anchors. Ubiqu...

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Detalles Bibliográficos
Autores principales: Colden, Melissa A., Kumar, Sushant, Munkhbileg, Bolormaa, Babushok, Daria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831232/
https://www.ncbi.nlm.nih.gov/pubmed/35154088
http://dx.doi.org/10.3389/fimmu.2021.830172

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