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Enhanced Immunomodulatory Effect of Intravenous Immunoglobulin by Fc Galactosylation and Nonfucosylation

Intravenous immunoglobulin (IVIG) is used as an immunomodulatory agent in the treatment of various autoimmune/inflammatory diseases although its mechanism of action remains elusive. Recently, nonfucosylated IgG has been shown to be preferentially bound to Fcγ receptor IIIa (FcγRIIIa) on circulating...

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Detalles Bibliográficos
Autores principales:	Mimura, Yusuke, Mimura-Kimura, Yuka, Saldova, Radka, Rudd, Pauline M., Jefferis, Roy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831331/ https://www.ncbi.nlm.nih.gov/pubmed/35154135 http://dx.doi.org/10.3389/fimmu.2022.818382

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