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SRPK2 Expression and Beta-Amyloid Accumulation Are Associated With BV2 Microglia Activation

INTRODUCTION: The extracellular deposition of β-amyloid (Aβ) is a pathological hallmark in Alzheimer's disease (AD), which induces microglial activation in the pathology of AD. The expression of serine/threonine-protein kinase 2 (SRPK2) is increased in the brain tissues of patients with AD. In...

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Detalles Bibliográficos
Autores principales: Tian, Ziqi, Zeng, Wenfang, Yan, Cuihuan, Li, Qiang, Li, Nan, Ruan, Lin, Li, Jie, Yao, Xiaoguang, Li, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831369/
https://www.ncbi.nlm.nih.gov/pubmed/35153686
http://dx.doi.org/10.3389/fnint.2021.742377