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Mesenchymal Lineage Heterogeneity Underlies Nonredundant Functions of Pancreatic Cancer–Associated Fibroblasts

Cancer-associated fibroblast (CAF) heterogeneity is increasingly appreciated, but the origins and functions of distinct CAF subtypes remain poorly understood. The abundant and transcriptionally diverse CAF population in pancreatic ductal adenocarcinoma (PDAC) is thought to arise from a common cell o...

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Detalles Bibliográficos
Autores principales: Helms, Erin J., Berry, Mark W., Chaw, R. Crystal, DuFort, Christopher C., Sun, Duanchen, Onate, M. Kathrina, Oon, Chet, Bhattacharyya, Sohinee, Sanford-Crane, Hannah, Horton, Wesley, Finan, Jennifer M., Sattler, Ariana, Makar, Rosemary, Dawson, David W., Xia, Zheng, Hingorani, Sunil R., Sherman, Mara H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831457/
https://www.ncbi.nlm.nih.gov/pubmed/34548310
http://dx.doi.org/10.1158/2159-8290.CD-21-0601