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MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma

The degree of metastatic disease varies widely among patients with cancer and affects clinical outcomes. However, the biological and functional differences that drive the extent of metastasis are poorly understood. We analyzed primary tumors and paired metastases using a multifluorescent lineage-lab...

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Detalles Bibliográficos
Autores principales: Maddipati, Ravikanth, Norgard, Robert J., Baslan, Timour, Rathi, Komal S., Zhang, Amy, Saeid, Asal, Higashihara, Taku, Wu, Feng, Kumar, Angad, Annamalai, Valli, Bhattacharya, Saurav, Raman, Pichai, Adkisson, Christian A., Pitarresi, Jason R., Wengyn, Maximilian D., Yamazoe, Taiji, Li, Jinyang, Balli, David, LaRiviere, Michael J., Ngo, Tuong-Vi C., Folkert, Ian W., Millstein, Ian D., Bermeo, Jonathan, Carpenter, Erica L., McAuliffe, John C., Oktay, Maja H., Brekken, Rolf A., Lowe, Scott W., Iacobuzio-Donahue, Christine A., Notta, Faiyaz, Stanger, Ben Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831468/
https://www.ncbi.nlm.nih.gov/pubmed/34551968
http://dx.doi.org/10.1158/2159-8290.CD-20-1826