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Lamina-associated polypeptide 2α is required for intranuclear MRTF-A activity

Myocardin-related transcription factor A (MRTF-A), a coactivator of serum response factor (SRF), regulates the expression of many cytoskeletal genes in response to cytoplasmic and nuclear actin dynamics. Here we describe a novel mechanism to regulate MRTF-A activity within the nucleus by showing tha...

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Detalles Bibliográficos
Autores principales:	Sidorenko, Ekaterina, Sokolova, Maria, Pennanen, Antti P., Kyheröinen, Salla, Posern, Guido, Foisner, Roland, Vartiainen, Maria K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831594/ https://www.ncbi.nlm.nih.gov/pubmed/35145145 http://dx.doi.org/10.1038/s41598-022-06135-5

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