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Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice

The pathophysiology of spinal cord injury (SCI) involves primary injury and secondary injury. Secondary injury is a major target for SCI therapy, whereas microglia play an important role in secondary injury. The immunoresponsive gene 1 (Irg-1) has been recorded as one of the most significantly upreg...

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Detalles Bibliográficos
Autores principales:	Ni, Libin, Xiao, Jian, Zhang, Di, Shao, Zhenxuan, Huang, Chongan, Wang, Sheng, Wu, Yaosen, Tian, Naifeng, Sun, Liaojun, Wu, Aimin, Zhou, Yifei, Wang, Xiangyang, Zhang, Xiaolei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831631/ https://www.ncbi.nlm.nih.gov/pubmed/35145070 http://dx.doi.org/10.1038/s41419-022-04592-4

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