CRISPR Interference Modules as Low-Burden Logic Inverters in Synthetic Circuits

CRISPR and CRISPRi systems have revolutionized our biological engineering capabilities by enabling the editing and regulation of virtually any gene, via customization of single guide RNA (sgRNA) sequences. CRISPRi modules can work as programmable logic inverters, in which the dCas9-sgRNA complex rep...

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Detalles Bibliográficos
Autores principales: Bellato, Massimo, Frusteri Chiacchiera, Angelica, Salibi, Elia, Casanova, Michela, De Marchi, Davide, Castagliuolo, Ignazio, Cusella De Angelis, Maria Gabriella, Magni, Paolo, Pasotti, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831695/
https://www.ncbi.nlm.nih.gov/pubmed/35155399
http://dx.doi.org/10.3389/fbioe.2021.743950

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