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A Tracing Model for the Evolutionary Equilibrium of Octoploids
Testing Hardy-Weinberg equilibrium (HWE) is a fundamental approach for inferring population diversity and evolution, but its application to octoploids containing eight chromosome sets has not well been justified. We derive a mathematical model to trace how genotype frequencies transmit from parental...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831725/ https://www.ncbi.nlm.nih.gov/pubmed/35154248 http://dx.doi.org/10.3389/fgene.2021.794907 |
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author | Wang, Jing Lv, Xuemin Feng, Li Dong, Ang Liang, Dan Wu, Rongling |
author_facet | Wang, Jing Lv, Xuemin Feng, Li Dong, Ang Liang, Dan Wu, Rongling |
author_sort | Wang, Jing |
collection | PubMed |
description | Testing Hardy-Weinberg equilibrium (HWE) is a fundamental approach for inferring population diversity and evolution, but its application to octoploids containing eight chromosome sets has not well been justified. We derive a mathematical model to trace how genotype frequencies transmit from parental to offspring generations in the natural populations of autooctoploids. We find that octoploids, including autooctolpoids undergoing double reduction, attach asymptotic HWE (aHWE) after 15 generations of random mating, in a contrast to diploids where one generation can assure exact equilibrium and, also, different from tetraploids that use 5 generations to reach aHWE. We develop a statistical procedure for testing aHWE in octoploids and apply it to analyze a real data set from octoploid switchgrass distributed in two ecologically different regions, demonstrating the usefulness of the test procedure. Our model provides a tool for studying the population genetic diversity of octoploids, inferring their evolutionary history, and identifying the ecological relationship of octoploid-genome structure with environmental adaptation. |
format | Online Article Text |
id | pubmed-8831725 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-88317252022-02-12 A Tracing Model for the Evolutionary Equilibrium of Octoploids Wang, Jing Lv, Xuemin Feng, Li Dong, Ang Liang, Dan Wu, Rongling Front Genet Genetics Testing Hardy-Weinberg equilibrium (HWE) is a fundamental approach for inferring population diversity and evolution, but its application to octoploids containing eight chromosome sets has not well been justified. We derive a mathematical model to trace how genotype frequencies transmit from parental to offspring generations in the natural populations of autooctoploids. We find that octoploids, including autooctolpoids undergoing double reduction, attach asymptotic HWE (aHWE) after 15 generations of random mating, in a contrast to diploids where one generation can assure exact equilibrium and, also, different from tetraploids that use 5 generations to reach aHWE. We develop a statistical procedure for testing aHWE in octoploids and apply it to analyze a real data set from octoploid switchgrass distributed in two ecologically different regions, demonstrating the usefulness of the test procedure. Our model provides a tool for studying the population genetic diversity of octoploids, inferring their evolutionary history, and identifying the ecological relationship of octoploid-genome structure with environmental adaptation. Frontiers Media S.A. 2022-01-28 /pmc/articles/PMC8831725/ /pubmed/35154248 http://dx.doi.org/10.3389/fgene.2021.794907 Text en Copyright © 2022 Wang, Lv, Feng, Dong, Liang and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Genetics Wang, Jing Lv, Xuemin Feng, Li Dong, Ang Liang, Dan Wu, Rongling A Tracing Model for the Evolutionary Equilibrium of Octoploids |
title | A Tracing Model for the Evolutionary Equilibrium of Octoploids |
title_full | A Tracing Model for the Evolutionary Equilibrium of Octoploids |
title_fullStr | A Tracing Model for the Evolutionary Equilibrium of Octoploids |
title_full_unstemmed | A Tracing Model for the Evolutionary Equilibrium of Octoploids |
title_short | A Tracing Model for the Evolutionary Equilibrium of Octoploids |
title_sort | tracing model for the evolutionary equilibrium of octoploids |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831725/ https://www.ncbi.nlm.nih.gov/pubmed/35154248 http://dx.doi.org/10.3389/fgene.2021.794907 |
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