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A Tracing Model for the Evolutionary Equilibrium of Octoploids

Testing Hardy-Weinberg equilibrium (HWE) is a fundamental approach for inferring population diversity and evolution, but its application to octoploids containing eight chromosome sets has not well been justified. We derive a mathematical model to trace how genotype frequencies transmit from parental...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Lv, Xuemin, Feng, Li, Dong, Ang, Liang, Dan, Wu, Rongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831725/
https://www.ncbi.nlm.nih.gov/pubmed/35154248
http://dx.doi.org/10.3389/fgene.2021.794907
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author Wang, Jing
Lv, Xuemin
Feng, Li
Dong, Ang
Liang, Dan
Wu, Rongling
author_facet Wang, Jing
Lv, Xuemin
Feng, Li
Dong, Ang
Liang, Dan
Wu, Rongling
author_sort Wang, Jing
collection PubMed
description Testing Hardy-Weinberg equilibrium (HWE) is a fundamental approach for inferring population diversity and evolution, but its application to octoploids containing eight chromosome sets has not well been justified. We derive a mathematical model to trace how genotype frequencies transmit from parental to offspring generations in the natural populations of autooctoploids. We find that octoploids, including autooctolpoids undergoing double reduction, attach asymptotic HWE (aHWE) after 15 generations of random mating, in a contrast to diploids where one generation can assure exact equilibrium and, also, different from tetraploids that use 5 generations to reach aHWE. We develop a statistical procedure for testing aHWE in octoploids and apply it to analyze a real data set from octoploid switchgrass distributed in two ecologically different regions, demonstrating the usefulness of the test procedure. Our model provides a tool for studying the population genetic diversity of octoploids, inferring their evolutionary history, and identifying the ecological relationship of octoploid-genome structure with environmental adaptation.
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spelling pubmed-88317252022-02-12 A Tracing Model for the Evolutionary Equilibrium of Octoploids Wang, Jing Lv, Xuemin Feng, Li Dong, Ang Liang, Dan Wu, Rongling Front Genet Genetics Testing Hardy-Weinberg equilibrium (HWE) is a fundamental approach for inferring population diversity and evolution, but its application to octoploids containing eight chromosome sets has not well been justified. We derive a mathematical model to trace how genotype frequencies transmit from parental to offspring generations in the natural populations of autooctoploids. We find that octoploids, including autooctolpoids undergoing double reduction, attach asymptotic HWE (aHWE) after 15 generations of random mating, in a contrast to diploids where one generation can assure exact equilibrium and, also, different from tetraploids that use 5 generations to reach aHWE. We develop a statistical procedure for testing aHWE in octoploids and apply it to analyze a real data set from octoploid switchgrass distributed in two ecologically different regions, demonstrating the usefulness of the test procedure. Our model provides a tool for studying the population genetic diversity of octoploids, inferring their evolutionary history, and identifying the ecological relationship of octoploid-genome structure with environmental adaptation. Frontiers Media S.A. 2022-01-28 /pmc/articles/PMC8831725/ /pubmed/35154248 http://dx.doi.org/10.3389/fgene.2021.794907 Text en Copyright © 2022 Wang, Lv, Feng, Dong, Liang and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Wang, Jing
Lv, Xuemin
Feng, Li
Dong, Ang
Liang, Dan
Wu, Rongling
A Tracing Model for the Evolutionary Equilibrium of Octoploids
title A Tracing Model for the Evolutionary Equilibrium of Octoploids
title_full A Tracing Model for the Evolutionary Equilibrium of Octoploids
title_fullStr A Tracing Model for the Evolutionary Equilibrium of Octoploids
title_full_unstemmed A Tracing Model for the Evolutionary Equilibrium of Octoploids
title_short A Tracing Model for the Evolutionary Equilibrium of Octoploids
title_sort tracing model for the evolutionary equilibrium of octoploids
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831725/
https://www.ncbi.nlm.nih.gov/pubmed/35154248
http://dx.doi.org/10.3389/fgene.2021.794907
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