Tourniquet‐induced lower limb ischemia/reperfusion reduces mitochondrial function by decreasing mitochondrial biogenesis in acute kidney injury in mice

The mechanisms by which lower limb ischemia/reperfusion induces acute kidney injury (AKI) remain largely uncharacterized. We hypothesized that tourniquet‐induced lower limb ischemia/reperfusion (TILLIR) would inhibit mitochondrial function in the renal cortex. We used a murine model to show that TIL...

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Detalles Bibliográficos
Autores principales: Packialakshmi, Balamurugan, Stewart, Ian J., Burmeister, David M., Feng, Yuanyi, McDaniel, Dennis P., Chung, Kevin K., Zhou, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831939/
https://www.ncbi.nlm.nih.gov/pubmed/35146957
http://dx.doi.org/10.14814/phy2.15181

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