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Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis

OBJECTIVE: Currently, the prevalence of CF (Cognitive Frailty) is not very clear, and the relationship between CF and its associated risk factors has not been accurately evaluated. Therefore, it is necessary to conduct a systematic review and meta-analysis further to understand CF's prevalence...

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Autores principales: Zhang, Tao, Ren, Yan, Shen, Ping, Jiang, Shixie, Yang, Yanrong, Wang, Yan, Li, Zheng, Yang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832102/
https://www.ncbi.nlm.nih.gov/pubmed/35153714
http://dx.doi.org/10.3389/fnagi.2021.755926
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author Zhang, Tao
Ren, Yan
Shen, Ping
Jiang, Shixie
Yang, Yanrong
Wang, Yan
Li, Zheng
Yang, Ying
author_facet Zhang, Tao
Ren, Yan
Shen, Ping
Jiang, Shixie
Yang, Yanrong
Wang, Yan
Li, Zheng
Yang, Ying
author_sort Zhang, Tao
collection PubMed
description OBJECTIVE: Currently, the prevalence of CF (Cognitive Frailty) is not very clear, and the relationship between CF and its associated risk factors has not been accurately evaluated. Therefore, it is necessary to conduct a systematic review and meta-analysis further to understand CF's prevalence and associated factors. METHODS: Embase, PubMed, Web of Science, Ovid, and Cochrane were systematically searched for articles exploring the prevalence of CF, the deadline of searching date was up to March 2021. For the prevalence of CF, the events of CF and the total number of patients in every included study were extracted to estimate the prevalence of CF. For associated factors of CF, Odds Ratios (ORs) with (corresponding) 95% confidence intervals (CIs) were used for estimations. RESULTS: Firstly, the estimated prevalence of CF I (Cognitive Frailty in the model I) was 16%, 95% CI (0.13–0.19), and the estimated prevalence of CF II (Cognitive Frailty in model II) was 6%, 95% CI (0.05–0.07). Secondly, both lower engagement in activities and age were calculated to be independent risk factors of CF, and the OR (95% CI) was 3.31 (2.28–4.81) and 1.10 (1.04–1.16), respectively. Finally, depression was also a prominent risk factor of CF, with the overall OR (95% CI) as 1.57 (1.32–1.87). CONCLUSION: CF was a high prevalence in community older. The various assessment scales and the different cutoff values of diagnostic criteria would affect the prevalence of CF. Lower engagement in activities, age, and depression was the risky factor of CF. SYSTEMATIC REVIEW REGISTRATION: http://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42019121369.
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spelling pubmed-88321022022-02-12 Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis Zhang, Tao Ren, Yan Shen, Ping Jiang, Shixie Yang, Yanrong Wang, Yan Li, Zheng Yang, Ying Front Aging Neurosci Aging Neuroscience OBJECTIVE: Currently, the prevalence of CF (Cognitive Frailty) is not very clear, and the relationship between CF and its associated risk factors has not been accurately evaluated. Therefore, it is necessary to conduct a systematic review and meta-analysis further to understand CF's prevalence and associated factors. METHODS: Embase, PubMed, Web of Science, Ovid, and Cochrane were systematically searched for articles exploring the prevalence of CF, the deadline of searching date was up to March 2021. For the prevalence of CF, the events of CF and the total number of patients in every included study were extracted to estimate the prevalence of CF. For associated factors of CF, Odds Ratios (ORs) with (corresponding) 95% confidence intervals (CIs) were used for estimations. RESULTS: Firstly, the estimated prevalence of CF I (Cognitive Frailty in the model I) was 16%, 95% CI (0.13–0.19), and the estimated prevalence of CF II (Cognitive Frailty in model II) was 6%, 95% CI (0.05–0.07). Secondly, both lower engagement in activities and age were calculated to be independent risk factors of CF, and the OR (95% CI) was 3.31 (2.28–4.81) and 1.10 (1.04–1.16), respectively. Finally, depression was also a prominent risk factor of CF, with the overall OR (95% CI) as 1.57 (1.32–1.87). CONCLUSION: CF was a high prevalence in community older. The various assessment scales and the different cutoff values of diagnostic criteria would affect the prevalence of CF. Lower engagement in activities, age, and depression was the risky factor of CF. SYSTEMATIC REVIEW REGISTRATION: http://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42019121369. Frontiers Media S.A. 2022-01-28 /pmc/articles/PMC8832102/ /pubmed/35153714 http://dx.doi.org/10.3389/fnagi.2021.755926 Text en Copyright © 2022 Zhang, Ren, Shen, Jiang, Yang, Wang, Li and Yang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Aging Neuroscience
Zhang, Tao
Ren, Yan
Shen, Ping
Jiang, Shixie
Yang, Yanrong
Wang, Yan
Li, Zheng
Yang, Ying
Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis
title Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis
title_full Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis
title_fullStr Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis
title_full_unstemmed Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis
title_short Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis
title_sort prevalence and associated risk factors of cognitive frailty: a systematic review and meta-analysis
topic Aging Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832102/
https://www.ncbi.nlm.nih.gov/pubmed/35153714
http://dx.doi.org/10.3389/fnagi.2021.755926
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