Gut HIF2α signaling is increased after VSG, and gut activation of HIF2α decreases weight, improves glucose, and increases GLP-1 secretion

Gastric bypass and vertical sleeve gastrectomy (VSG) remain the most potent and durable treatments for obesity and type 2 diabetes but are also associated with iron deficiency. The transcription factor HIF2α, which regulates iron absorption in the duodenum, increases following these surgeries. Incre...

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Detalles Bibliográficos
Autores principales: Evers, Simon S., Shao, Yikai, Ramakrishnan, Sadeesh K., Shin, Jae Hoon, Bozadjieva-Kramer, Nadejda, Irmler, Martin, Stemmer, Kerstin, Sandoval, Darleen A., Shah, Yatrik M., Seeley, Randy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832374/
https://www.ncbi.nlm.nih.gov/pubmed/35045308
http://dx.doi.org/10.1016/j.celrep.2021.110270

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