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Adolescents and Young Adults Knowledge, Adherence and Experiences While on Antiretroviral Therapy in a Tertiary Hospital in Lagos, Nigeria: A Mixed-Method Study

In Nigeria, there is a paucity of data on knowledge and experiences of adolescents and young adults (AYAs) with HIV and ART, as well as their challenges maintaining optimal adherence. A mixed-method study was carried out between August and September 2018 among AYAs attending Lagos University Teachin...

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Autores principales: Aderemi-Williams, Roseline Iberi, Razaq, Ayomikun Rofiat, Abah, Isaac Okoh, Opanuga, Olabisi Oluranti, Akanmu, Alani Sulaimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832484/
https://www.ncbi.nlm.nih.gov/pubmed/34881662
http://dx.doi.org/10.1177/23259582211062754
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author Aderemi-Williams, Roseline Iberi
Razaq, Ayomikun Rofiat
Abah, Isaac Okoh
Opanuga, Olabisi Oluranti
Akanmu, Alani Sulaimon
author_facet Aderemi-Williams, Roseline Iberi
Razaq, Ayomikun Rofiat
Abah, Isaac Okoh
Opanuga, Olabisi Oluranti
Akanmu, Alani Sulaimon
author_sort Aderemi-Williams, Roseline Iberi
collection PubMed
description In Nigeria, there is a paucity of data on knowledge and experiences of adolescents and young adults (AYAs) with HIV and ART, as well as their challenges maintaining optimal adherence. A mixed-method study was carried out between August and September 2018 among AYAs attending Lagos University Teaching Hospital, Nigeria. Data collection was via AYAs' hospital records, standardized questionnaires, and in-depth interviews (IDIs). The 4-day ACTG tool was used to measure adherence. Collected data were analyzed descriptively. Assessment of 34 AYAs comprising 18 (52.9%) males with 28 (82.4%) students revealed an overall knowledge score about ART and its effect of 73.6%. Twenty-five (73.5%) had poor knowledge of the development of resistant strains of HIV due to non-adherence recorded. Optimal adherence (≥95%) was recorded in 20 (58.8%) AYAs. IDI produced 4 themes: (i) reasons for non-adherence, (ii) ensuring optimal adherence, (iii) Social support systems and disclosure, and (iv) stigmatization. Our study provided formative data and revealed areas for intervention to improve knowledge and adherence to ART.
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spelling pubmed-88324842022-02-12 Adolescents and Young Adults Knowledge, Adherence and Experiences While on Antiretroviral Therapy in a Tertiary Hospital in Lagos, Nigeria: A Mixed-Method Study Aderemi-Williams, Roseline Iberi Razaq, Ayomikun Rofiat Abah, Isaac Okoh Opanuga, Olabisi Oluranti Akanmu, Alani Sulaimon J Int Assoc Provid AIDS Care Original Research Article In Nigeria, there is a paucity of data on knowledge and experiences of adolescents and young adults (AYAs) with HIV and ART, as well as their challenges maintaining optimal adherence. A mixed-method study was carried out between August and September 2018 among AYAs attending Lagos University Teaching Hospital, Nigeria. Data collection was via AYAs' hospital records, standardized questionnaires, and in-depth interviews (IDIs). The 4-day ACTG tool was used to measure adherence. Collected data were analyzed descriptively. Assessment of 34 AYAs comprising 18 (52.9%) males with 28 (82.4%) students revealed an overall knowledge score about ART and its effect of 73.6%. Twenty-five (73.5%) had poor knowledge of the development of resistant strains of HIV due to non-adherence recorded. Optimal adherence (≥95%) was recorded in 20 (58.8%) AYAs. IDI produced 4 themes: (i) reasons for non-adherence, (ii) ensuring optimal adherence, (iii) Social support systems and disclosure, and (iv) stigmatization. Our study provided formative data and revealed areas for intervention to improve knowledge and adherence to ART. SAGE Publications 2021-12-09 /pmc/articles/PMC8832484/ /pubmed/34881662 http://dx.doi.org/10.1177/23259582211062754 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research Article
Aderemi-Williams, Roseline Iberi
Razaq, Ayomikun Rofiat
Abah, Isaac Okoh
Opanuga, Olabisi Oluranti
Akanmu, Alani Sulaimon
Adolescents and Young Adults Knowledge, Adherence and Experiences While on Antiretroviral Therapy in a Tertiary Hospital in Lagos, Nigeria: A Mixed-Method Study
title Adolescents and Young Adults Knowledge, Adherence and Experiences While on Antiretroviral Therapy in a Tertiary Hospital in Lagos, Nigeria: A Mixed-Method Study
title_full Adolescents and Young Adults Knowledge, Adherence and Experiences While on Antiretroviral Therapy in a Tertiary Hospital in Lagos, Nigeria: A Mixed-Method Study
title_fullStr Adolescents and Young Adults Knowledge, Adherence and Experiences While on Antiretroviral Therapy in a Tertiary Hospital in Lagos, Nigeria: A Mixed-Method Study
title_full_unstemmed Adolescents and Young Adults Knowledge, Adherence and Experiences While on Antiretroviral Therapy in a Tertiary Hospital in Lagos, Nigeria: A Mixed-Method Study
title_short Adolescents and Young Adults Knowledge, Adherence and Experiences While on Antiretroviral Therapy in a Tertiary Hospital in Lagos, Nigeria: A Mixed-Method Study
title_sort adolescents and young adults knowledge, adherence and experiences while on antiretroviral therapy in a tertiary hospital in lagos, nigeria: a mixed-method study
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832484/
https://www.ncbi.nlm.nih.gov/pubmed/34881662
http://dx.doi.org/10.1177/23259582211062754
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