Cargando…

Expression and Characterization of Relaxin Family Peptide Receptor 1 Variants

G-protein coupled receptors (GPCR) transduce extracellular stimuli into the cell interior and are thus centrally involved in almost all physiological-neuronal processes. This essential function and association with many diseases or pathological conditions explain why GPCRs are one of the priority ta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Speck, David, Kleinau, Gunnar, Meininghaus, Mark, Erbe, Antje, Einfeldt, Alexandra, Szczepek, Michal, Scheerer, Patrick, Pütter, Vera
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832513/ https://www.ncbi.nlm.nih.gov/pubmed/35153771 http://dx.doi.org/10.3389/fphar.2021.826112

Ejemplares similares

The Trace Amine-Associated Receptor 1 Agonist 3-Iodothyronamine Induces Biased Signaling at the Serotonin 1b Receptor
por: Bräunig, Julia, et al.
Publicado: (2018)

Angiotensin and Endothelin Receptor Structures With Implications for Signaling Regulation and Pharmacological Targeting
por: Speck, David, et al.
Publicado: (2022)

Binding, Thermodynamics, and Selectivity of a Non-peptide Antagonist to the Melanocortin-4 Receptor
por: Saleh, Noureldin, et al.
Publicado: (2018)

Synthetic short-chain peptide analogues of H1 relaxin lack affinity for the RXFP1 receptor and relaxin-like bioactivity. Clues to a better understanding of relaxin agonist design
por: D'Ercole, Annunziata, et al.
Publicado: (2022)

Evolution of the relaxin-like peptide family
por: Wilkinson, Tracey N, et al.
Publicado: (2005)

Comparative Genomic Characterization of Relaxin Peptide Family in Cattle and Buffalo
por: Rehman, Muhammad Saif-ur, et al.
Publicado: (2022)

Signal Transduction and Pathogenic Modifications at the Melanocortin-4 Receptor: A Structural Perspective
por: Heyder, Nicolas, et al.
Publicado: (2019)

Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin
por: Bruell, Shoni, et al.
Publicado: (2017)

Synthesis of fluorescent analogs of relaxin family peptides and their preliminary in vitro and in vivo characterization
por: Chan, Linda J., et al.
Publicado: (2013)

Relaxin as a Therapeutic Target for the Cardiovascular Complications of Diabetes
por: Ng, Hooi Hooi, et al.
Publicado: (2018)

Activation of Relaxin Family Receptor 1 from Different Mammalian Species by Relaxin Peptide and Small-Molecule Agonist ML290
por: Huang, Zaohua, et al.
Publicado: (2015)

Relaxin-Family Peptide Receptors 1 and 2 Are Fully Functional in the Bovine
por: Dai, Yanzhenzi, et al.
Publicado: (2017)

Development of a selective agonist for relaxin family peptide receptor 3
por: Wei, Dian, et al.
Publicado: (2017)

Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2
por: Esteban-Lopez, Maria, et al.
Publicado: (2022)

Molecular Effects of Auto-Antibodies on Angiotensin II Type 1 Receptor Signaling and Cell Proliferation
por: Philippe, Aurélie, et al.
Publicado: (2022)

Relaxin-3/RXFP3 networks: an emerging target for the treatment of depression and other neuropsychiatric diseases?
por: Smith, Craig M., et al.
Publicado: (2014)

Relaxin-like Gonad-Stimulating Peptides in Asteroidea
por: Mita, Masatoshi
Publicado: (2023)

The Pathogenic TSH β-Subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR
por: Kalveram, Laura, et al.
Publicado: (2019)

Relaxin'
Publicado: (1983)

Relaxin
por: DeCherney, Alan H.
Publicado: (1982)

Structural Complexity and Plasticity of Signaling Regulation at the Melanocortin-4 Receptor
por: Kleinau, Gunnar, et al.
Publicado: (2020)

Mechanism for insulin-like peptide 5 distinguishing the homologous relaxin family peptide receptor 3 and 4
por: Hu, Meng-Jun, et al.
Publicado: (2016)

New Insights into Ligand-Receptor Pairing and Coevolution of Relaxin Family Peptides and Their Receptors in Teleosts
por: Good, Sara, et al.
Publicado: (2012)

The relaxin peptide family – potential future hope for neuroprotective therapy? A short review
por: Nistor, Marius, et al.
Publicado: (2018)

Expression of the relaxin family peptide 4 receptor by enterochromaffin cells of the mouse large intestine
por: Koo, Ada, et al.
Publicado: (2022)

Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4)
por: Chen, Yan, et al.
Publicado: (2023)

Relaxin Can Mediate Its Anti-Fibrotic Effects by Targeting the Myofibroblast NLRP3 Inflammasome at the Level of Caspase-1
por: Pinar, Anita A., et al.
Publicado: (2020)

Characterizing relaxin receptor expression and exploring relaxin’s effect on tissue remodeling/fibrosis in the human bladder
por: Diaz, Edward C., et al.
Publicado: (2020)

Investigation of Naturally Occurring Single-Nucleotide Variants in Human TAAR1
por: Mühlhaus, Jessica, et al.
Publicado: (2017)

Non-Functional Trace Amine-Associated Receptor 1 Variants in Patients With Mental Disorders
por: Rutigliano, Grazia, et al.
Publicado: (2019)

Insights into Basal Signaling Regulation, Oligomerization, and Structural Organization of the Human G-Protein Coupled Receptor 83
por: Müller, Anne, et al.
Publicado: (2016)

Erratum to “New Insights into Ligand-Receptor Pairing and Coevolution of Relaxin Family Peptides and Their Receptors in Teleosts”
por: Good, Sara, et al.
Publicado: (2013)

The relaxin family peptide receptor 1 (RXFP1): An emerging player in human health and disease
por: Chen, Ting‐Yun, et al.
Publicado: (2020)

SAT026 Melanocortin Receptors In The Earliest Chordates?
por: Ji, Ren-Lei, et al.
Publicado: (2023)

Chronic Exposure to Cigarette Smoke Affects the Ileum and Colon of Guinea Pigs Differently. Relaxin (RLX-2, Serelaxin) Prevents Most Local Damage
por: Traini, Chiara, et al.
Publicado: (2022)

Characterization of relaxin 3 and its receptors in chicken: Evidence for relaxin 3 acting as a novel pituitary hormone
por: Lv, Can, et al.
Publicado: (2022)

The Anti-fibrotic Actions of Relaxin Are Mediated Through a NO-sGC-cGMP-Dependent Pathway in Renal Myofibroblasts In Vitro and Enhanced by the NO Donor, Diethylamine NONOate
por: Wang, Chao, et al.
Publicado: (2016)

Structural–Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at Work
por: Kleinau, Gunnar, et al.
Publicado: (2017)

Is the Neuropeptide PEN a Ligand of GPR83?
por: Giesecke, Yvonne, et al.
Publicado: (2023)

Evolution of the Relaxin/Insulin-Like Gene Family in Anthropoid Primates
por: Arroyo, José Ignacio, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5i49v8g5nj5b5af4o5vshfit7r