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Tumor-suppressive circRHOBTB3 is excreted out of cells via exosome to sustain colorectal cancer cell fitness

BACKGROUND & AIMS: To clarify the biological roles, circularization process and secretion pathway of circRHOBTB3 in colorectal cancer (CRC) progression. METHODS: We performed a comprehensive analysis of circRNA levels in serum exosomes from multiple types of cancer patients in public databases a...

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Detalles Bibliográficos
Autores principales:	Chen, Chaoyi, Yu, Hongfei, Han, Fengyan, Lai, Xuan, Ye, Kehong, Lei, Siqin, Mai, Minglang, Lai, Maode, Zhang, Honghe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832727/ https://www.ncbi.nlm.nih.gov/pubmed/35148775 http://dx.doi.org/10.1186/s12943-022-01511-1

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