A validation study of potential prognostic DNA methylation biomarkers in patients with acute myeloid leukemia using a custom DNA methylation sequencing panel

BACKGROUND: Multiple studies have reported the prognostic impact of DNA methylation changes in acute myeloid leukemia (AML). However, these epigenetic markers have not been thoroughly validated and therefore are still not considered in clinical practice. Hence, we aimed to independently verify resul...

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Detalles Bibliográficos
Autores principales: Šestáková, Šárka, Cerovská, Ela, Šálek, Cyril, Kundrát, Dávid, Ježíšková, Ivana, Folta, Adam, Mayer, Jiří, Ráčil, Zdeněk, Cetkovský, Petr, Remešová, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832751/
https://www.ncbi.nlm.nih.gov/pubmed/35148810
http://dx.doi.org/10.1186/s13148-022-01242-6

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