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Genomic correlation, shared loci, and causal relationship between obesity and polycystic ovary syndrome: a large-scale genome-wide cross-trait analysis

BACKGROUND: The comorbidity between polycystic ovary syndrome (PCOS) and obesity has long been observed in clinical settings, but their shared genetic basis remains unclear. METHODS: Leveraging summary statistics of large-scale GWAS(s) conducted in European-ancestry populations on body mass index (a...

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Detalles Bibliográficos
Autores principales: Liu, Qianwen, Zhu, Zhaozhong, Kraft, Peter, Deng, Qiaolin, Stener-Victorin, Elisabet, Jiang, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832782/
https://www.ncbi.nlm.nih.gov/pubmed/35144605
http://dx.doi.org/10.1186/s12916-022-02238-y

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