Determining if T cell antigens are naturally processed and presented on HLA class I molecules

BACKGROUND: Determining T cell responses to naturally processed and presented antigens is a critical immune correlate to determine efficacy of an investigational immunotherapeutic in clinical trials. In most cases, minimal epitopes and HLA restriction elements are unknown. RESULTS: Here, we detail t...

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Detalles Bibliográficos
Autores principales: Friedman, Jay, Gunti, Sreenivasulu, Lee, Maxwell, Bai, Ke, Hinrichs, Christian, Allen, Clint T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832792/
https://www.ncbi.nlm.nih.gov/pubmed/35148673
http://dx.doi.org/10.1186/s12865-022-00478-4

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