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Evolution of CDK1 Paralog Specializations in a Lineage With Fast Developing Planktonic Embryos

The active site of the essential CDK1 kinase is generated by core structural elements, among which the PSTAIRE motif in the critical αC-helix, is universally conserved in the single CDK1 ortholog of all metazoans. We report serial CDK1 duplications in the chordate, Oikopleura. Paralog diversificatio...

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Detalles Bibliográficos
Autores principales: Ma, Xiaofei, Øvrebø, Jan Inge, Thompson, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832800/
https://www.ncbi.nlm.nih.gov/pubmed/35155443
http://dx.doi.org/10.3389/fcell.2021.770939

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