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Evolution of CDK1 Paralog Specializations in a Lineage With Fast Developing Planktonic Embryos
The active site of the essential CDK1 kinase is generated by core structural elements, among which the PSTAIRE motif in the critical αC-helix, is universally conserved in the single CDK1 ortholog of all metazoans. We report serial CDK1 duplications in the chordate, Oikopleura. Paralog diversificatio...
Autores principales: | Ma, Xiaofei, Øvrebø, Jan Inge, Thompson, Eric M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832800/ https://www.ncbi.nlm.nih.gov/pubmed/35155443 http://dx.doi.org/10.3389/fcell.2021.770939 |
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