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Comparative outcomes of pure laparoscopic and open donor right hepatectomy: the first report from a Southeast Asian transplant center

BACKGROUND: Pure laparoscopic donor right hepatectomy (PLDRH) can provide better operative outcomes for the donor than conventional open donor right hepatectomy (CODRH). However, the complexity of the procedure typically makes transplant teams reluctant to perform it, especially in low-volume transp...

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Autores principales: Lapisatepun, Worakitti, Junrungsee, Sunhawit, Chotirosniramit, Anon, Udomsin, Kanya, Lapisatepun, Warangkana, Chanthima, Phuriphong, Boonsri, Settapong, Lorsomradee, Suraphong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832827/
https://www.ncbi.nlm.nih.gov/pubmed/35148721
http://dx.doi.org/10.1186/s12893-022-01507-0
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author Lapisatepun, Worakitti
Junrungsee, Sunhawit
Chotirosniramit, Anon
Udomsin, Kanya
Lapisatepun, Warangkana
Chanthima, Phuriphong
Boonsri, Settapong
Lorsomradee, Suraphong
author_facet Lapisatepun, Worakitti
Junrungsee, Sunhawit
Chotirosniramit, Anon
Udomsin, Kanya
Lapisatepun, Warangkana
Chanthima, Phuriphong
Boonsri, Settapong
Lorsomradee, Suraphong
author_sort Lapisatepun, Worakitti
collection PubMed
description BACKGROUND: Pure laparoscopic donor right hepatectomy (PLDRH) can provide better operative outcomes for the donor than conventional open donor right hepatectomy (CODRH). However, the complexity of the procedure typically makes transplant teams reluctant to perform it, especially in low-volume transplant centers. We compared the outcomes of PLDRH and CODRH to demonstrate the feasibility of PLDRH in a low-volume transplant program. METHODS: We carried out a retrospective study of adult living donor liver transplantation in Chiang Mai University Hospital from January 2015 to March 2021. The patients were divided into a PLDRH group and a CODRH group. Baseline characteristics, operative parameters, and postoperative complications of donors and recipients were compared between the two groups. RESULTS: Thirty patients underwent donor hepatectomy between the dates selected (9 PLDRH patients and 21 CODRH patients). The baseline characteristics of the 2 groups were not significantly different. The median graft volume of the PLDRH group was 693.8 mL, which was not significantly different from that of the CODRH group (726.5 mL) The PLDRH group had a longer operative time than the CODRH group, but the difference was not statistically significant (487.5 min vs 425.0 min, p = 0.197). The overall complication rate was not significantly different between the two groups (33.3% vs 22.2%, p = 0.555). Additionally, for the recipients, the incidence of major complications was not significantly different between the groups (71.3 vs 55.6%, p = 0.792). CONCLUSION: Even in the context of this low-volume transplant program, whose staff have a high level of experience in minimally invasive hepatobiliary surgery, PLDRH showed similar results to CODRH in terms of perioperative outcomes for donors and recipients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12893-022-01507-0.
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spelling pubmed-88328272022-02-15 Comparative outcomes of pure laparoscopic and open donor right hepatectomy: the first report from a Southeast Asian transplant center Lapisatepun, Worakitti Junrungsee, Sunhawit Chotirosniramit, Anon Udomsin, Kanya Lapisatepun, Warangkana Chanthima, Phuriphong Boonsri, Settapong Lorsomradee, Suraphong BMC Surg Research Article BACKGROUND: Pure laparoscopic donor right hepatectomy (PLDRH) can provide better operative outcomes for the donor than conventional open donor right hepatectomy (CODRH). However, the complexity of the procedure typically makes transplant teams reluctant to perform it, especially in low-volume transplant centers. We compared the outcomes of PLDRH and CODRH to demonstrate the feasibility of PLDRH in a low-volume transplant program. METHODS: We carried out a retrospective study of adult living donor liver transplantation in Chiang Mai University Hospital from January 2015 to March 2021. The patients were divided into a PLDRH group and a CODRH group. Baseline characteristics, operative parameters, and postoperative complications of donors and recipients were compared between the two groups. RESULTS: Thirty patients underwent donor hepatectomy between the dates selected (9 PLDRH patients and 21 CODRH patients). The baseline characteristics of the 2 groups were not significantly different. The median graft volume of the PLDRH group was 693.8 mL, which was not significantly different from that of the CODRH group (726.5 mL) The PLDRH group had a longer operative time than the CODRH group, but the difference was not statistically significant (487.5 min vs 425.0 min, p = 0.197). The overall complication rate was not significantly different between the two groups (33.3% vs 22.2%, p = 0.555). Additionally, for the recipients, the incidence of major complications was not significantly different between the groups (71.3 vs 55.6%, p = 0.792). CONCLUSION: Even in the context of this low-volume transplant program, whose staff have a high level of experience in minimally invasive hepatobiliary surgery, PLDRH showed similar results to CODRH in terms of perioperative outcomes for donors and recipients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12893-022-01507-0. BioMed Central 2022-02-11 /pmc/articles/PMC8832827/ /pubmed/35148721 http://dx.doi.org/10.1186/s12893-022-01507-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Lapisatepun, Worakitti
Junrungsee, Sunhawit
Chotirosniramit, Anon
Udomsin, Kanya
Lapisatepun, Warangkana
Chanthima, Phuriphong
Boonsri, Settapong
Lorsomradee, Suraphong
Comparative outcomes of pure laparoscopic and open donor right hepatectomy: the first report from a Southeast Asian transplant center
title Comparative outcomes of pure laparoscopic and open donor right hepatectomy: the first report from a Southeast Asian transplant center
title_full Comparative outcomes of pure laparoscopic and open donor right hepatectomy: the first report from a Southeast Asian transplant center
title_fullStr Comparative outcomes of pure laparoscopic and open donor right hepatectomy: the first report from a Southeast Asian transplant center
title_full_unstemmed Comparative outcomes of pure laparoscopic and open donor right hepatectomy: the first report from a Southeast Asian transplant center
title_short Comparative outcomes of pure laparoscopic and open donor right hepatectomy: the first report from a Southeast Asian transplant center
title_sort comparative outcomes of pure laparoscopic and open donor right hepatectomy: the first report from a southeast asian transplant center
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832827/
https://www.ncbi.nlm.nih.gov/pubmed/35148721
http://dx.doi.org/10.1186/s12893-022-01507-0
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