Somatic mutational profiles and germline polygenic risk scores in human cancer

BACKGROUND: The mutational profile of cancer reflects the activity of the mutagenic processes which have been operative throughout the lineage of the cancer cell. These processes leave characteristic profiles of somatic mutations called mutational signatures. Mutational signatures, including single-...

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Detalles Bibliográficos
Autores principales: Liu, Yuxi, Gusev, Alexander, Heng, Yujing J., Alexandrov, Ludmil B., Kraft, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832866/
https://www.ncbi.nlm.nih.gov/pubmed/35144655
http://dx.doi.org/10.1186/s13073-022-01016-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832866/
https://www.ncbi.nlm.nih.gov/pubmed/35144655
http://dx.doi.org/10.1186/s13073-022-01016-y

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