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Tracheal Stenosis After Prolonged Intubation Due to COVID-19

OBJECTIVES: The authors aimed to evaluate the characteristics and management outcomes of patients who developed tracheal stenosis after invasive mechanical ventilation (IMV) due to COVID-19. DESIGN, SETTING, AND PARTICIPANTS: The data of 7 patients with tracheal stenosis and 201 patients without tra...

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Autores principales: Ayten, Omer, Iscanli, Insa Gul Ekiz, Canoglu, Kadir, Ozdemir, Cengiz, Saylan, Bengü, Caliskan, Tayfun, Akin, Hasan, Tezel, Cağatay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832874/
https://www.ncbi.nlm.nih.gov/pubmed/35283040
http://dx.doi.org/10.1053/j.jvca.2022.02.009
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author Ayten, Omer
Iscanli, Insa Gul Ekiz
Canoglu, Kadir
Ozdemir, Cengiz
Saylan, Bengü
Caliskan, Tayfun
Akin, Hasan
Tezel, Cağatay
author_facet Ayten, Omer
Iscanli, Insa Gul Ekiz
Canoglu, Kadir
Ozdemir, Cengiz
Saylan, Bengü
Caliskan, Tayfun
Akin, Hasan
Tezel, Cağatay
author_sort Ayten, Omer
collection PubMed
description OBJECTIVES: The authors aimed to evaluate the characteristics and management outcomes of patients who developed tracheal stenosis after invasive mechanical ventilation (IMV) due to COVID-19. DESIGN, SETTING, AND PARTICIPANTS: The data of 7 patients with tracheal stenosis and 201 patients without tracheal stenosis after IMV due to COVID-19 between March 2020 and October 2021 were retrospectively analyzed. INTERVENTIONS: Flexible bronchoscopy was performed for the diagnosis of tracheal stenosis and the evaluation of the treatment's effectiveness, and rigid bronchoscopy was applied for the dilatation of tracheal stenosis. MEASUREMENTS AND MAIN RESULTS: In the follow-up period, tracheal stenosis was observed in 7 of 208 patients (2 women, 5 men; 3.3%). The patients were divided into 2 groups as patients with tracheal stenosis (n = 7) and patients without tracheal stenosis (n = 201). There were no statistically significant differences between the 2 groups in terms of age, sex, body mass index, and comorbidities (p > 0.05). The mean duration of IMV of the patients with tracheal stenosis was longer than patients without tracheal stenosis (27.9 ± 13 v 11.2 ± 9 days, p < 0.0001, respectively). Three (43%) of the stenoses were web-like and 4 (57%) of them were complex-type stenosis. The mean length of the stenoses was 1.81 ± 0.82 cm. Three of the patients were treated successfully with bronchoscopic dilatation, and 4 of them were treated with tracheal resection. CONCLUSIONS: Tracheal stenosis developed in 7 of 208 (3.3%) patients with COVID-19 who were treated with IMV. The most important characteristic of patients with tracheal stenosis was prolonged IMV support.
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spelling pubmed-88328742022-02-14 Tracheal Stenosis After Prolonged Intubation Due to COVID-19 Ayten, Omer Iscanli, Insa Gul Ekiz Canoglu, Kadir Ozdemir, Cengiz Saylan, Bengü Caliskan, Tayfun Akin, Hasan Tezel, Cağatay J Cardiothorac Vasc Anesth Original Article OBJECTIVES: The authors aimed to evaluate the characteristics and management outcomes of patients who developed tracheal stenosis after invasive mechanical ventilation (IMV) due to COVID-19. DESIGN, SETTING, AND PARTICIPANTS: The data of 7 patients with tracheal stenosis and 201 patients without tracheal stenosis after IMV due to COVID-19 between March 2020 and October 2021 were retrospectively analyzed. INTERVENTIONS: Flexible bronchoscopy was performed for the diagnosis of tracheal stenosis and the evaluation of the treatment's effectiveness, and rigid bronchoscopy was applied for the dilatation of tracheal stenosis. MEASUREMENTS AND MAIN RESULTS: In the follow-up period, tracheal stenosis was observed in 7 of 208 patients (2 women, 5 men; 3.3%). The patients were divided into 2 groups as patients with tracheal stenosis (n = 7) and patients without tracheal stenosis (n = 201). There were no statistically significant differences between the 2 groups in terms of age, sex, body mass index, and comorbidities (p > 0.05). The mean duration of IMV of the patients with tracheal stenosis was longer than patients without tracheal stenosis (27.9 ± 13 v 11.2 ± 9 days, p < 0.0001, respectively). Three (43%) of the stenoses were web-like and 4 (57%) of them were complex-type stenosis. The mean length of the stenoses was 1.81 ± 0.82 cm. Three of the patients were treated successfully with bronchoscopic dilatation, and 4 of them were treated with tracheal resection. CONCLUSIONS: Tracheal stenosis developed in 7 of 208 (3.3%) patients with COVID-19 who were treated with IMV. The most important characteristic of patients with tracheal stenosis was prolonged IMV support. Elsevier Inc. 2022-08 2022-02-11 /pmc/articles/PMC8832874/ /pubmed/35283040 http://dx.doi.org/10.1053/j.jvca.2022.02.009 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Article
Ayten, Omer
Iscanli, Insa Gul Ekiz
Canoglu, Kadir
Ozdemir, Cengiz
Saylan, Bengü
Caliskan, Tayfun
Akin, Hasan
Tezel, Cağatay
Tracheal Stenosis After Prolonged Intubation Due to COVID-19
title Tracheal Stenosis After Prolonged Intubation Due to COVID-19
title_full Tracheal Stenosis After Prolonged Intubation Due to COVID-19
title_fullStr Tracheal Stenosis After Prolonged Intubation Due to COVID-19
title_full_unstemmed Tracheal Stenosis After Prolonged Intubation Due to COVID-19
title_short Tracheal Stenosis After Prolonged Intubation Due to COVID-19
title_sort tracheal stenosis after prolonged intubation due to covid-19
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832874/
https://www.ncbi.nlm.nih.gov/pubmed/35283040
http://dx.doi.org/10.1053/j.jvca.2022.02.009
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