Cargando…

A Reevaluation of the Tolerability and Effects of Single-Dose Ivermectin Treatment on Onchocerca volvulus Microfilariae in the Skin and Eyes in Eastern Ghana

Mass administration of ivermectin (IVM) has significantly reduced onchocerciasis prevalence, intensity, and morbidity in most endemic areas. Most IVM clinical trials were performed long ago in persons with high-intensity infections that are uncommon in West Africa today. This cohort treatment study...

Descripción completa

Detalles Bibliográficos
Autores principales:	Opoku, Nicholas O., Gyasi, Michael E., Doe, Felix, Lew, Daphne, Hong, Augustine R., Chithenga, Sithembele, Fischer, Peter U., King, Christopher L., Weil, Gary J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Tropical Medicine and Hygiene 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832884/ https://www.ncbi.nlm.nih.gov/pubmed/34844204 http://dx.doi.org/10.4269/ajtmh.21-0859

Ejemplares similares

Motile Onchocerca volvulus Microfilariae in the Anterior Chamber of the Eye
por: Gyasi, Michael E., et al.
Publicado: (2020)

Phenotypic Evidence of Emerging Ivermectin Resistance in Onchocerca volvulus
por: Osei-Atweneboana, Mike Y., et al.
Publicado: (2011)

Assessing Onchocerca volvulus Intensity of Infection and Genetic Diversity Using Mitochondrial Genome Sequencing of Single Microfilariae Obtained before and after Ivermectin Treatment
por: Hedtke, Shannon M., et al.
Publicado: (2023)

Genetic Selection of Low Fertile Onchocerca volvulus by Ivermectin Treatment
por: Bourguinat, Catherine, et al.
Publicado: (2007)

Ivermectin Resistance in Onchocerca volvulus: Toward a Genetic Basis
por: Lustigman, Sara, et al.
Publicado: (2007)

Procedure for Handling and Storage of Onchocerca volvulus Microfilariae Obtained from Skin Snips for Downstream Genetic Work
por: Hedtke, Shannon M., et al.
Publicado: (2023)

Effect of Ivermectin Treatment on the Frequency of Seizures in Persons with Epilepsy Infected with Onchocerca volvulus
por: Dusabimana, Alfred, et al.
Publicado: (2020)

A Randomized, Single-Ascending-Dose, Ivermectin-Controlled, Double-Blind Study of Moxidectin in Onchocerca volvulus Infection
por: Awadzi, Kwablah, et al.
Publicado: (2014)

Reproductive Status of Onchocerca volvulus after Ivermectin Treatment in an Ivermectin-Naïve and a Frequently Treated Population from Cameroon
por: Nana-Djeunga, Hugues C., et al.
Publicado: (2014)

A randomized, open-label study of the tolerability and efficacy of one or three daily doses of ivermectin plus diethylcarbamazine and albendazole (IDA) versus one dose of ivermectin plus albendazole (IA) for treatment of onchocerciasis
por: Opoku, Nicholas O., et al.
Publicado: (2023)

Extracts of Euphorbia hirta Linn. (Euphorbiaceae) and Rauvolfia vomitoria Afzel (Apocynaceae) demonstrate activities against Onchocerca volvulus Microfilariae in vitro
por: Attah, Simon K, et al.
Publicado: (2013)

Dynamics of Onchocerca volvulus Microfilarial Densities after Ivermectin Treatment in an Ivermectin-naïve and a Multiply Treated Population from Cameroon
por: Pion, Sébastien D. S., et al.
Publicado: (2013)

Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial
por: Opoku, Nicholas O, et al.
Publicado: (2018)

Cutaneous Distribution and Circadian Rhythm of Onchocerca lupi Microfilariae in Dogs
por: Otranto, Domenico, et al.
Publicado: (2013)

Pharmacokinetics of oral moxidectin in individuals with Onchocerca volvulus infection
por: Tan, Beesan, et al.
Publicado: (2022)

Contribution of migrant coffee labourers infected with Onchocerca volvulus to the maintenance of the microfilarial reservoir in an ivermectin-treated area of Mexico
por: Rodríguez-Pérez, Mario A, et al.
Publicado: (2007)

Ivermectin Treatment Response in Onchocerca Volvulus Infected Persons with Epilepsy: A Three-Country Short Cohort Study
por: Dusabimana, Alfred, et al.
Publicado: (2020)

Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment
por: Abong, Raphael Awah, et al.
Publicado: (2020)

A qPCR to quantify Wolbachia from few Onchocerca volvulus microfilariae as a surrogate for adult worm histology in clinical trials of antiwolbachial drugs
por: Schlabe, Stefan, et al.
Publicado: (2022)

Factors Associated with Ivermectin Non-Compliance and Its Potential Role in Sustaining Onchocerca volvulus Transmission in the West Region of Cameroon
por: Senyonjo, Laura, et al.
Publicado: (2016)

Correction to: Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment
por: Abong, Raphael Awah, et al.
Publicado: (2021)

Molecular cloning of an immunodominant antigen of Onchocerca volvulus
Publicado: (1988)

Interruption of Onchocerca volvulus transmission in Northern Venezuela
por: Convit, Jacinto, et al.
Publicado: (2013)

The genome of Onchocerca volvulus, agent of river blindness
por: Cotton, James A., et al.
Publicado: (2016)

Onchocerca volvulus Mimicking Metastatic Breast Carcinoma
por: Nava, Victor E., et al.
Publicado: (2020)

Incidental Detection of Onchocerca Microfilariae in Donkeys (Equus asinus) in Italy: Report of Four Cases
por: Papini, Roberto Amerigo, et al.
Publicado: (2020)

Histopathological evaluation of Onchocerca volvulus nodules by microscopy and by digital image analysis for the study of macrofilaricidal drug efficacy
por: Fischer, Kerstin, et al.
Publicado: (2023)

Elimination of Onchocerca volvulus Transmission in the Huehuetenango Focus of Guatemala
por: Cruz-Ortiz, Nancy, et al.
Publicado: (2012)

The mitogenome of Onchocerca volvulus from the Brazilian Amazonia focus
por: Crainey, James L, et al.
Publicado: (2016)

Neurological manifestations in Onchocerca volvulus infection: A review
por: Hotterbeekx, An, et al.
Publicado: (2019)

Multimodal biomarker discovery for active Onchocerca volvulus infection
por: Lagatie, Ole, et al.
Publicado: (2021)

Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals
por: Arndts, Kathrin, et al.
Publicado: (2015)

Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity
por: Doyle, Stephen R., et al.
Publicado: (2017)

Transmission indices and microfilariae prevalence in human population prior to mass drug administration with ivermectin and albendazole in the Gomoa District of Ghana
por: Aboagye-Antwi, Fred, et al.
Publicado: (2015)

Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection
por: Bakajika, Didier, et al.
Publicado: (2022)

Ongoing Transmission of Onchocerca volvulus after 25 Years of Annual Ivermectin Mass Treatments in the Vina du Nord River Valley, in North Cameroon
por: Eisenbarth, Albert, et al.
Publicado: (2016)

Onchocerca volvulus-specific antibody and cellular responses in onchocerciasis patients treated annually with ivermectin for 30 years and exposed to parasite transmission in central Togo
por: Johanns, Saskia I., et al.
Publicado: (2022)

Criteria for the differentiation between young and old Onchocerca volvulus filariae
por: Specht, Sabine, et al.
Publicado: (2009)

Individual exposure to Simulium bites and intensity of Onchocerca volvulus infection
por: Jacobi, C A, et al.
Publicado: (2010)

Newly acquired Onchocerca volvulus filariae after doxycycline treatment
por: Specht, Sabine, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_4vha96c24ev2rvn7cp3brp2s35