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Systematic screening reveals synergistic interactions that overcome MAPK inhibitor resistance in cancer cells

OBJECTIVE: Effective adjuvant therapeutic strategies are urgently needed to overcome MAPK inhibitor (MAPKi) resistance, which is one of the most common forms of resistance that has emerged in many types of cancers. Here, we aimed to systematically identify the genetic interactions underlying MAPKi r...

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Detalles Bibliográficos
Autores principales: Yu, Yu, Tao, Minzhen, Xu, Libin, Cao, Lei, Le, Baoyu, An, Na, Dong, Jilin, Xu, Yajie, Yang, Baoxing, Li, Wei, Liu, Bing, Wu, Qiong, Lu, Yinying, Xie, Zhen, Lian, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832956/
https://www.ncbi.nlm.nih.gov/pubmed/34106558
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0560