iASPP suppresses Gp78-mediated TMCO1 degradation to maintain Ca(2+) homeostasis and control tumor growth and drug resistance

Ca(2+) release from the endoplasmic reticulum (ER) is an essential event in the modulation of Ca(2+) homeostasis, which is coordinated by multiple biological processes, ranging from cell proliferation to apoptosis. Deregulated Ca(2+) homeostasis is linked with various cancer hallmarks; thus, uncover...

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Detalles Bibliográficos
Autores principales: Zheng, Shanliang, Zhao, Dong, Hou, Guixue, Zhao, Song, Zhang, Wenxin, Wang, Xingwen, Li, Li, Lin, Liang, Tang, Tie-Shan, Hu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832991/
https://www.ncbi.nlm.nih.gov/pubmed/35121659
http://dx.doi.org/10.1073/pnas.2111380119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832991/
https://www.ncbi.nlm.nih.gov/pubmed/35121659
http://dx.doi.org/10.1073/pnas.2111380119

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