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iASPP suppresses Gp78-mediated TMCO1 degradation to maintain Ca(2+) homeostasis and control tumor growth and drug resistance
Ca(2+) release from the endoplasmic reticulum (ER) is an essential event in the modulation of Ca(2+) homeostasis, which is coordinated by multiple biological processes, ranging from cell proliferation to apoptosis. Deregulated Ca(2+) homeostasis is linked with various cancer hallmarks; thus, uncover...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832991/ https://www.ncbi.nlm.nih.gov/pubmed/35121659 http://dx.doi.org/10.1073/pnas.2111380119 |