Fluctuations in T cell receptor and pMHC interactions regulate T cell activation

Adaptive immune responses depend on interactions between T cell receptors (TCRs) and peptide major histocompatibility complex (pMHC) ligands located on the surface of T cells and antigen presenting cells (APCs), respectively. As TCRs and pMHCs are often only present at low copy numbers their interac...

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Detalles Bibliográficos
Autores principales: Egan, Joseph R., Abu-Shah, Enas, Dushek, Omer, Elliott, Tim, MacArthur, Ben D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Life Sciences–Mathematics interface
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833104/
https://www.ncbi.nlm.nih.gov/pubmed/35135295
http://dx.doi.org/10.1098/rsif.2021.0589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833104/
https://www.ncbi.nlm.nih.gov/pubmed/35135295
http://dx.doi.org/10.1098/rsif.2021.0589

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