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Fluctuations in T cell receptor and pMHC interactions regulate T cell activation
Adaptive immune responses depend on interactions between T cell receptors (TCRs) and peptide major histocompatibility complex (pMHC) ligands located on the surface of T cells and antigen presenting cells (APCs), respectively. As TCRs and pMHCs are often only present at low copy numbers their interac...
Autores principales: | Egan, Joseph R., Abu-Shah, Enas, Dushek, Omer, Elliott, Tim, MacArthur, Ben D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833104/ https://www.ncbi.nlm.nih.gov/pubmed/35135295 http://dx.doi.org/10.1098/rsif.2021.0589 |
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