Cargando…

A sudden creatinine increase: A case report

Creatinine and estimated glomerular filtration rate (eGFR) are first-line laboratory parameters in the diagnosis of various renal diseases. In recent decades, cystatin C (cysC) has furthered the laboratory repertoire regarding renal status assessment and has been implemented in many clinical guideli...

Descripción completa

Detalles Bibliográficos
Autores principales: Strasser, Bernhard, Strasser, Sebastian, Tomasits, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Society of Medical Biochemistry and Laboratory Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833249/
https://www.ncbi.nlm.nih.gov/pubmed/35210930
http://dx.doi.org/10.11613/BM.2022.011002
_version_ 1784648889381421056
author Strasser, Bernhard
Strasser, Sebastian
Tomasits, Josef
author_facet Strasser, Bernhard
Strasser, Sebastian
Tomasits, Josef
author_sort Strasser, Bernhard
collection PubMed
description Creatinine and estimated glomerular filtration rate (eGFR) are first-line laboratory parameters in the diagnosis of various renal diseases. In recent decades, cystatin C (cysC) has furthered the laboratory repertoire regarding renal status assessment and has been implemented in many clinical guidelines. Accordingly, with the establishment of cysC as a renal routine biomarker, further opportunities for assessing eGFR have been attained. Nevertheless, various limitations are still associated with cysC and creatinine analysis. Preanalytical errors could cause false results in both biomarkers. In our case, we were confronted with implausibly elevated creatinine levels due to preanalytical errors.
format Online
Article
Text
id pubmed-8833249
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Croatian Society of Medical Biochemistry and Laboratory Medicine
record_format MEDLINE/PubMed
spelling pubmed-88332492022-02-23 A sudden creatinine increase: A case report Strasser, Bernhard Strasser, Sebastian Tomasits, Josef Biochem Med (Zagreb) Preanalytical Mysteries Creatinine and estimated glomerular filtration rate (eGFR) are first-line laboratory parameters in the diagnosis of various renal diseases. In recent decades, cystatin C (cysC) has furthered the laboratory repertoire regarding renal status assessment and has been implemented in many clinical guidelines. Accordingly, with the establishment of cysC as a renal routine biomarker, further opportunities for assessing eGFR have been attained. Nevertheless, various limitations are still associated with cysC and creatinine analysis. Preanalytical errors could cause false results in both biomarkers. In our case, we were confronted with implausibly elevated creatinine levels due to preanalytical errors. Croatian Society of Medical Biochemistry and Laboratory Medicine 2022-02-15 2022-02-15 /pmc/articles/PMC8833249/ /pubmed/35210930 http://dx.doi.org/10.11613/BM.2022.011002 Text en Croatian Society of Medical Biochemistry and Laboratory Medicine. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Preanalytical Mysteries
Strasser, Bernhard
Strasser, Sebastian
Tomasits, Josef
A sudden creatinine increase: A case report
title A sudden creatinine increase: A case report
title_full A sudden creatinine increase: A case report
title_fullStr A sudden creatinine increase: A case report
title_full_unstemmed A sudden creatinine increase: A case report
title_short A sudden creatinine increase: A case report
title_sort sudden creatinine increase: a case report
topic Preanalytical Mysteries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833249/
https://www.ncbi.nlm.nih.gov/pubmed/35210930
http://dx.doi.org/10.11613/BM.2022.011002
work_keys_str_mv AT strasserbernhard asuddencreatinineincreaseacasereport
AT strassersebastian asuddencreatinineincreaseacasereport
AT tomasitsjosef asuddencreatinineincreaseacasereport
AT strasserbernhard suddencreatinineincreaseacasereport
AT strassersebastian suddencreatinineincreaseacasereport
AT tomasitsjosef suddencreatinineincreaseacasereport