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Status Epilepticus as a Life-Threatening Manifestation of Myxedema Crisis
Myxedema coma is a rare life-threatening emergency that usually presents in the elderly during the winter months. The neurological changes caused by uncontrolled hypothyroidism may precipitate seizure activity and its deleterious consequences. A 65-year-old homeless man with a history of non-Hodgkin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833291/ https://www.ncbi.nlm.nih.gov/pubmed/35165605 http://dx.doi.org/10.7759/cureus.21155 |
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author | Somoza-Cano, Francisco J Al Armashi, Abdul Rahman Patell, Kanchi Hammad, Faris Ravakhah, Keyvan |
author_facet | Somoza-Cano, Francisco J Al Armashi, Abdul Rahman Patell, Kanchi Hammad, Faris Ravakhah, Keyvan |
author_sort | Somoza-Cano, Francisco J |
collection | PubMed |
description | Myxedema coma is a rare life-threatening emergency that usually presents in the elderly during the winter months. The neurological changes caused by uncontrolled hypothyroidism may precipitate seizure activity and its deleterious consequences. A 65-year-old homeless man with a history of non-Hodgkin lymphoma in remission for over 20 years presented to the emergency department (ED) following an episode of syncope. His physical examination was remarkable for hypothermia and bradycardia. Shortly after the admission, he had two tonic-clonic seizures with sphincter relaxation and no recovery between the convulsions. His thyroid-stimulating hormone (TSH) level was 304 uIU/ml. He received appropriate treatment for his condition and was discharged after a full recovery. This case illustrates the catastrophic consequences of long-term uncontrolled hypothyroidism. A high index of clinical suspicion is essential for beginning prompt hormone supplementation in such patients. |
format | Online Article Text |
id | pubmed-8833291 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-88332912022-02-13 Status Epilepticus as a Life-Threatening Manifestation of Myxedema Crisis Somoza-Cano, Francisco J Al Armashi, Abdul Rahman Patell, Kanchi Hammad, Faris Ravakhah, Keyvan Cureus Endocrinology/Diabetes/Metabolism Myxedema coma is a rare life-threatening emergency that usually presents in the elderly during the winter months. The neurological changes caused by uncontrolled hypothyroidism may precipitate seizure activity and its deleterious consequences. A 65-year-old homeless man with a history of non-Hodgkin lymphoma in remission for over 20 years presented to the emergency department (ED) following an episode of syncope. His physical examination was remarkable for hypothermia and bradycardia. Shortly after the admission, he had two tonic-clonic seizures with sphincter relaxation and no recovery between the convulsions. His thyroid-stimulating hormone (TSH) level was 304 uIU/ml. He received appropriate treatment for his condition and was discharged after a full recovery. This case illustrates the catastrophic consequences of long-term uncontrolled hypothyroidism. A high index of clinical suspicion is essential for beginning prompt hormone supplementation in such patients. Cureus 2022-01-12 /pmc/articles/PMC8833291/ /pubmed/35165605 http://dx.doi.org/10.7759/cureus.21155 Text en Copyright © 2022, Somoza-Cano et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Endocrinology/Diabetes/Metabolism Somoza-Cano, Francisco J Al Armashi, Abdul Rahman Patell, Kanchi Hammad, Faris Ravakhah, Keyvan Status Epilepticus as a Life-Threatening Manifestation of Myxedema Crisis |
title | Status Epilepticus as a Life-Threatening Manifestation of Myxedema Crisis |
title_full | Status Epilepticus as a Life-Threatening Manifestation of Myxedema Crisis |
title_fullStr | Status Epilepticus as a Life-Threatening Manifestation of Myxedema Crisis |
title_full_unstemmed | Status Epilepticus as a Life-Threatening Manifestation of Myxedema Crisis |
title_short | Status Epilepticus as a Life-Threatening Manifestation of Myxedema Crisis |
title_sort | status epilepticus as a life-threatening manifestation of myxedema crisis |
topic | Endocrinology/Diabetes/Metabolism |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833291/ https://www.ncbi.nlm.nih.gov/pubmed/35165605 http://dx.doi.org/10.7759/cureus.21155 |
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