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Alkaline Diuresis as Treatment for 2,4-D Dimethylamine Herbicide Intoxication
Acute intoxication with 2,4-D dimethylamine is rare, often fatal and can cause signs and symptoms in different organ systems. This case report describes the effectiveness of alkaline diuresis as a life-saving treatment for chlorophenoxy intoxication, especially in healthcare facilities without acces...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SMC Media Srl
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833296/ https://www.ncbi.nlm.nih.gov/pubmed/35169579 http://dx.doi.org/10.12890/2022_003126 |
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author | Badu, Apolonia Berenika Cempakadewi, Ade Ajeng Budihardja, Brigitta Marcia Ake, Anselmus |
author_facet | Badu, Apolonia Berenika Cempakadewi, Ade Ajeng Budihardja, Brigitta Marcia Ake, Anselmus |
author_sort | Badu, Apolonia Berenika |
collection | PubMed |
description | Acute intoxication with 2,4-D dimethylamine is rare, often fatal and can cause signs and symptoms in different organ systems. This case report describes the effectiveness of alkaline diuresis as a life-saving treatment for chlorophenoxy intoxication, especially in healthcare facilities without access to haemodialysis. A patient had attempted suicide by ingesting 2,4-D dimethylamine, with toxic effects on the central and peripheral nervous systems, and the gastrointestinal and respiratory systems. However, she significantly improved after alkaline diuresis, accompanied by resuscitation, decontamination of the gastrointestinal system, and supportive therapies. LEARNING POINTS: With no known of antidote, 2,4-D dimethylamine intoxication can be fatal if not treated promptly. Alkaline diuresis can be a life-saving treatment, especially in rural area with no access to haemodialysis. Treatment with alkaline diuresis can give a good result in patients who present with severe intoxication. |
format | Online Article Text |
id | pubmed-8833296 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SMC Media Srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-88332962022-02-14 Alkaline Diuresis as Treatment for 2,4-D Dimethylamine Herbicide Intoxication Badu, Apolonia Berenika Cempakadewi, Ade Ajeng Budihardja, Brigitta Marcia Ake, Anselmus Eur J Case Rep Intern Med Articles Acute intoxication with 2,4-D dimethylamine is rare, often fatal and can cause signs and symptoms in different organ systems. This case report describes the effectiveness of alkaline diuresis as a life-saving treatment for chlorophenoxy intoxication, especially in healthcare facilities without access to haemodialysis. A patient had attempted suicide by ingesting 2,4-D dimethylamine, with toxic effects on the central and peripheral nervous systems, and the gastrointestinal and respiratory systems. However, she significantly improved after alkaline diuresis, accompanied by resuscitation, decontamination of the gastrointestinal system, and supportive therapies. LEARNING POINTS: With no known of antidote, 2,4-D dimethylamine intoxication can be fatal if not treated promptly. Alkaline diuresis can be a life-saving treatment, especially in rural area with no access to haemodialysis. Treatment with alkaline diuresis can give a good result in patients who present with severe intoxication. SMC Media Srl 2022-01-19 /pmc/articles/PMC8833296/ /pubmed/35169579 http://dx.doi.org/10.12890/2022_003126 Text en © EFIM 2022 This article is licensed under a Commons Attribution Non-Commercial 4.0 License |
spellingShingle | Articles Badu, Apolonia Berenika Cempakadewi, Ade Ajeng Budihardja, Brigitta Marcia Ake, Anselmus Alkaline Diuresis as Treatment for 2,4-D Dimethylamine Herbicide Intoxication |
title | Alkaline Diuresis as Treatment for 2,4-D Dimethylamine Herbicide Intoxication |
title_full | Alkaline Diuresis as Treatment for 2,4-D Dimethylamine Herbicide Intoxication |
title_fullStr | Alkaline Diuresis as Treatment for 2,4-D Dimethylamine Herbicide Intoxication |
title_full_unstemmed | Alkaline Diuresis as Treatment for 2,4-D Dimethylamine Herbicide Intoxication |
title_short | Alkaline Diuresis as Treatment for 2,4-D Dimethylamine Herbicide Intoxication |
title_sort | alkaline diuresis as treatment for 2,4-d dimethylamine herbicide intoxication |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833296/ https://www.ncbi.nlm.nih.gov/pubmed/35169579 http://dx.doi.org/10.12890/2022_003126 |
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