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Dysphagia as a Rare Presentation of Cervical Cancer with Mediastinal Metastasis
Dysphagia has a broad aetiology and so it is essential to identify the precise cause. Cervical cancer metastasis is distinctive in that it usually involves local lymph node invasion; however, approximately 1% of cases have mediastinal involvement, which can cause severe compressive symptoms in rare...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SMC Media Srl
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833304/ https://www.ncbi.nlm.nih.gov/pubmed/35169582 http://dx.doi.org/10.12890/2022_003136 |
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author | Singh, Vinit Gor, Dhairya Azad, Sarah Ricca, Anthony Xu, Yiqing Meghal, Trishala |
author_facet | Singh, Vinit Gor, Dhairya Azad, Sarah Ricca, Anthony Xu, Yiqing Meghal, Trishala |
author_sort | Singh, Vinit |
collection | PubMed |
description | Dysphagia has a broad aetiology and so it is essential to identify the precise cause. Cervical cancer metastasis is distinctive in that it usually involves local lymph node invasion; however, approximately 1% of cases have mediastinal involvement, which can cause severe compressive symptoms in rare situations. To highlight an uncommon severe manifestation of cervical cancer relapse, we describe a case of dysphagia in a woman with a history of cervical cancer. After a thorough investigation that included endoscopy, endoscopy with ultrasound, an oesophagogram and fine needle aspiration, we eventually reached the diagnosis of mediastinal metastatic cervical cancer. Following interventions, the patient’s condition gradually improved, both clinically and radiographically. LEARNING POINTS: Mediastinal lymph node enlargement causing dysphagia can be a presenting sign of a metastatic lesion from treated cervical cancer. A PEG tube is helpful in relieving dysphagia caused by metastatic mediastinal lymph node enlargement and as bridge for nutrition during chemotherapy. The VEGF inhibitor bevacizumab can be used in advanced metastatic cervical cancer. Check-point inhibitors like pembrolizumab can be used in metastatic cervical cancer. |
format | Online Article Text |
id | pubmed-8833304 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SMC Media Srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-88333042022-02-14 Dysphagia as a Rare Presentation of Cervical Cancer with Mediastinal Metastasis Singh, Vinit Gor, Dhairya Azad, Sarah Ricca, Anthony Xu, Yiqing Meghal, Trishala Eur J Case Rep Intern Med Articles Dysphagia has a broad aetiology and so it is essential to identify the precise cause. Cervical cancer metastasis is distinctive in that it usually involves local lymph node invasion; however, approximately 1% of cases have mediastinal involvement, which can cause severe compressive symptoms in rare situations. To highlight an uncommon severe manifestation of cervical cancer relapse, we describe a case of dysphagia in a woman with a history of cervical cancer. After a thorough investigation that included endoscopy, endoscopy with ultrasound, an oesophagogram and fine needle aspiration, we eventually reached the diagnosis of mediastinal metastatic cervical cancer. Following interventions, the patient’s condition gradually improved, both clinically and radiographically. LEARNING POINTS: Mediastinal lymph node enlargement causing dysphagia can be a presenting sign of a metastatic lesion from treated cervical cancer. A PEG tube is helpful in relieving dysphagia caused by metastatic mediastinal lymph node enlargement and as bridge for nutrition during chemotherapy. The VEGF inhibitor bevacizumab can be used in advanced metastatic cervical cancer. Check-point inhibitors like pembrolizumab can be used in metastatic cervical cancer. SMC Media Srl 2022-01-24 /pmc/articles/PMC8833304/ /pubmed/35169582 http://dx.doi.org/10.12890/2022_003136 Text en © EFIM 2022 This article is licensed under a Commons Attribution Non-Commercial 4.0 License |
spellingShingle | Articles Singh, Vinit Gor, Dhairya Azad, Sarah Ricca, Anthony Xu, Yiqing Meghal, Trishala Dysphagia as a Rare Presentation of Cervical Cancer with Mediastinal Metastasis |
title | Dysphagia as a Rare Presentation of Cervical Cancer with Mediastinal Metastasis |
title_full | Dysphagia as a Rare Presentation of Cervical Cancer with Mediastinal Metastasis |
title_fullStr | Dysphagia as a Rare Presentation of Cervical Cancer with Mediastinal Metastasis |
title_full_unstemmed | Dysphagia as a Rare Presentation of Cervical Cancer with Mediastinal Metastasis |
title_short | Dysphagia as a Rare Presentation of Cervical Cancer with Mediastinal Metastasis |
title_sort | dysphagia as a rare presentation of cervical cancer with mediastinal metastasis |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833304/ https://www.ncbi.nlm.nih.gov/pubmed/35169582 http://dx.doi.org/10.12890/2022_003136 |
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