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Pancreatic Cancer Organoids in the Field of Precision Medicine: A Review of Literature and Experience on Drug Sensitivity Testing with Multiple Readouts and Synergy Scoring
SIMPLE SUMMARY: New treatments are urgently needed for pancreatic ductal adenocarcinoma because it is one of the most aggressive and lethal cancers, detected too late and resistant to conventional chemotherapy. Tumors in most patients feature a similar set of core mutations but so far it has not bee...
Autores principales: | Mäkinen, Lotta, Vähä-Koskela, Markus, Juusola, Matilda, Mustonen, Harri, Wennerberg, Krister, Hagström, Jaana, Puolakkainen, Pauli, Seppänen, Hanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833348/ https://www.ncbi.nlm.nih.gov/pubmed/35158794 http://dx.doi.org/10.3390/cancers14030525 |
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