Cargando…

Neoadjuvant Chemotherapy of Patients with Early Breast Cancer Is Associated with Increased Detection of Disseminated Tumor Cells in the Bone Marrow

SIMPLE SUMMARY: Disseminated tumor cells (DTCs) present in the bone marrow of breast cancer patients are an indicator of minimal residual disease and micrometastatic spread. These cells can already be found at the earliest disease stages and are associated with poorer outcomes. In preclinical models...

Descripción completa

Detalles Bibliográficos
Autores principales:	Volmer, Léa, Koch, André, Matovina, Sabine, Dannehl, Dominik, Weiss, Martin, Welker, Ganna, Hahn, Markus, Engler, Tobias, Wallwiener, Markus, Walter, Christina Barbara, Oberlechner, Ernst, Brucker, Sara Yvonne, Pantel, Klaus, Hartkopf, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833450/ https://www.ncbi.nlm.nih.gov/pubmed/35158902 http://dx.doi.org/10.3390/cancers14030635

Ejemplares similares

Feasibility of Adjuvant Treatment with Abemaciclib—Real-World Data from a Large German Breast Center
por: Dannehl, Dominik, et al.
Publicado: (2022)

Association between 21-gene-assay and detection of disseminated tumor cells in patients with early breast cancer: results from the IRMA trial
por: Volmer, Léa L., et al.
Publicado: (2023)

Comparison of Biosimilar Trastuzumab ABP 980 with Reference Trastuzumab in Neoadjuvant Therapy for HER2-positive Breast Cancer – an Analysis of a Large University Breast Cancer Centre
por: Matovina, Sabine, et al.
Publicado: (2022)

Microfluidic Isolation of Disseminated Tumor Cells from the Bone Marrow of Breast Cancer Patients
por: Volmer, Léa L., et al.
Publicado: (2023)

The presence and prognostic impact of apoptotic and nonapoptotic disseminated tumor cells in the bone marrow of primary breast cancer patients after neoadjuvant chemotherapy
por: Hartkopf, Andreas Daniel, et al.
Publicado: (2013)

Simultaneous Detection of Disseminated and Circulating Tumor Cells in Primary Breast Cancer Patients
por: Hartkopf, Andreas D., et al.
Publicado: (2016)

Recurrence Score(®) Result Impacts Treatment Decisions in Hormone Receptor-Positive, HER2-Negative Patients with Early Breast Cancer in a Real-World Setting—Results of the IRMA Trial
por: Dannehl, Dominik, et al.
Publicado: (2022)

Evaluation of sonographic detectability of different markers within an in vitro simulation model of the axilla
por: Guergan, Selin, et al.
Publicado: (2021)

Which Patients Do We Need to Test for BRCA1/2 Mutation? Feasibility of Adjuvant Olaparib Treatment in Early Breast Cancer–Real-World Data from Two Large German Breast Centers
por: Dannehl, Dominik, et al.
Publicado: (2023)

Prognostic relevance of induced and spontaneous apoptosis of disseminated tumor cells in primary breast cancer patients
por: Krawczyk, Natalia, et al.
Publicado: (2014)

The Clinical Relevance of the NATALEE Study: Application of the NATALEE Criteria to a Real-World Cohort from Two Large German Breast Cancer Centers
por: Schäffler, Henning, et al.
Publicado: (2023)

The Brustkrebs-Studien.de website for breast cancer patients: User acceptance of a German internet portal offering information on the disease and treatment options, and a clinical trials matching service
por: Wallwiener, Markus, et al.
Publicado: (2010)

Implementation of an Electronic Patient-Reported Outcome App for Health-Related Quality of Life in Breast Cancer Patients: Evaluation and Acceptability Analysis in a Two-Center Prospective Trial
por: Graf, Joachim, et al.
Publicado: (2022)

Tumor-Free Resection Margin Distance in the Surgical Treatment of Node-Negative Squamous Cell Cancer of the Vulva Has No Impact on Survival: Analysis of a Large Patient Cohort in a Tertiary Care Center
por: Taran, Florin Andrei, et al.
Publicado: (2023)

Lysine-urethane-based tissue adhesion for mastectomy—an approach to reducing the seroma rate?
por: Boeer, B., et al.
Publicado: (2020)

Distribution of the 21-Gene Breast Recurrence Score in Patients with Primary Breast Cancer in Germany
por: Walter, Vincent P., et al.
Publicado: (2020)

Multidisciplinary breast centres in Germany: a review and update of quality assurance through benchmarking and certification
por: Wallwiener, Markus, et al.
Publicado: (2012)

A Three-Dimensional Organoid Model of Primary Breast Cancer to Investigate the Effects of Oncolytic Virotherapy
por: Carter, Mary E., et al.
Publicado: (2022)

The Lack of Evidence for an Association between Cancer Biomarker Conversion Patterns and CTC-Status in Patients with Metastatic Breast Cancer
por: Stefanovic, Stefan, et al.
Publicado: (2020)

Cut-Off Analysis of CTC Change under Systemic Therapy for Defining Early Therapy Response in Metastatic Breast Cancer
por: Deutsch, Thomas M., et al.
Publicado: (2020)

Measuring the Time to Deterioration for Health-Related Quality of Life in Patients With Metastatic Breast Cancer Using a Web-Based Monitoring Application: Longitudinal Cohort Study
por: Brusniak, Katharina, et al.
Publicado: (2021)

Advancing Cancer Therapy Predictions with Patient-Derived Organoid Models of Metastatic Breast Cancer
por: Önder, Cansu E., et al.
Publicado: (2023)

Presence of apoptotic and nonapoptotic disseminated tumor cells reflects the response to neoadjuvant systemic therapy in breast cancer
por: Fehm, Tanja, et al.
Publicado: (2006)

Measurement of tumour size with mammography, sonography and magnetic resonance imaging as compared to histological tumour size in primary breast cancer
por: Gruber, Ines V, et al.
Publicado: (2013)

ERalpha-status of disseminated tumour cells in bone marrow of primary breast cancer patients
por: Fehm, Tanja, et al.
Publicado: (2008)

Re-augmentation of the Axilla Using a Turn-Over Flap – a New Approach for the Surgical Treatment of Secondary Lymphedema After Breast Cancer
por: Marx, Mario, et al.
Publicado: (2020)

Electronic-Based Patient-Reported Outcomes: Willingness, Needs, and Barriers in Adjuvant and Metastatic Breast Cancer Patients
por: Hartkopf, Andreas D, et al.
Publicado: (2017)

HER2-targeted therapy influences CTC status in metastatic breast cancer
por: Deutsch, Thomas M., et al.
Publicado: (2020)

Protein Profiling of Breast Carcinomas Reveals Expression of Immune-Suppressive Factors and Signatures Relevant for Patient Outcome
por: Ruoff, Felix, et al.
Publicado: (2022)

The impact of HER2 phenotype of circulating tumor cells in metastatic breast cancer: a retrospective study in 107 patients
por: Wallwiener, Markus, et al.
Publicado: (2015)

Effectiveness and cost-effectiveness of an electronic mindfulness-based intervention (eMBI) on maternal mental health during pregnancy: the mindmom study protocol for a randomized controlled clinical trial
por: Müller, Mitho, et al.
Publicado: (2020)

How Negative Is Negative Information
por: Simoes, Elisabeth, et al.
Publicado: (2021)

Circulating miR-200 Family and CTCs in Metastatic Breast Cancer before, during, and after a New Line of Systemic Treatment
por: Fischer, Chiara, et al.
Publicado: (2022)

Reliability of an e-PRO Tool of EORTC QLQ-C30 for Measurement of Health-Related Quality of Life in Patients With Breast Cancer: Prospective Randomized Trial
por: Wallwiener, Markus, et al.
Publicado: (2017)

Breast cancer patient-derived microtumors resemble tumor heterogeneity and enable protein-based stratification and functional validation of individualized drug treatment
por: Anderle, Nicole, et al.
Publicado: (2023)

The impact of rehabilitation sport on breast cancer-related lymphoedema and quality of life
por: Boeer, Bettina, et al.
Publicado: (2022)

Estrogen, progesterone, and human epidermal growth factor receptor 2 discordance between primary and metastatic breast cancer
por: Walter, Vincent, et al.
Publicado: (2020)

Influence of zoledronic acid on disseminated tumor cells in bone marrow and survival: results of a prospective clinical trial
por: Banys, Malgorzata, et al.
Publicado: (2013)

Comparative evaluation of cell-free tumor DNA in blood and disseminated tumor cells in bone marrow of patients with primary breast cancer
por: Schwarzenbach, Heidi, et al.
Publicado: (2009)

Circulating miR-200 family as predictive markers during systemic therapy of metastatic breast cancer
por: Fischer, Chiara, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_khms3efp3br33i3hok3da8ckla