Targeted Deletion of Kindlin-2 in Mouse Mammary Glands Inhibits Tumor Growth, Invasion, and Metastasis Downstream of a TGF-β/EGF Oncogenic Signaling Pathway

SIMPLE SUMMARY: Studies from our group and others have established Kindlin-2 that is expressed in the cancer cells as a major driver of tumor progression and metastasis in breast cancer (BC). The role of Kindlin-2 that is expressed in the mammary glands (tumor microenvironment) in the pathogenesis o...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Rana, Priyanka S., Alkrekshi, Akram, Bialkowska, Katarzyna, Markovic, Vesna, Schiemann, William P., Plow, Edward F., Pluskota, Elzbieta, Sossey-Alaoui, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833458/
https://www.ncbi.nlm.nih.gov/pubmed/35158908
http://dx.doi.org/10.3390/cancers14030639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833458/
https://www.ncbi.nlm.nih.gov/pubmed/35158908
http://dx.doi.org/10.3390/cancers14030639

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