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Epigenetic Approaches to Overcome Fluoropyrimidines Resistance in Solid Tumors

SIMPLE SUMMARY: Fluoropyrimidines represent the backbone of many combination chemotherapy regimens for the treatment of solid cancers but are still associated with toxicity and mechanisms of resistance. In this review, we focused on the epigenetic modifiers histone deacetylase inhibitors (HDACis) an...

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Detalles Bibliográficos
Autores principales: Grumetti, Laura, Lombardi, Rita, Iannelli, Federica, Pucci, Biagio, Avallone, Antonio, Di Gennaro, Elena, Budillon, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833539/
https://www.ncbi.nlm.nih.gov/pubmed/35158962
http://dx.doi.org/10.3390/cancers14030695