Cargando…

RBM22, a Key Player of Pre-mRNA Splicing and Gene Expression Regulation, Is Altered in Cancer

SIMPLE SUMMARY: RBM22 is a gene that encodes an essential RNA-Binding Protein involved in pre-mRNA splicing and transcription, with a DNA-binding function. This dual RNA/DNA-Binding activity provides a new insight of the regulation of gene expression by RBM22. Many studies have reported that RBM22 i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Soubise, Benoît, Jiang, Yan, Douet-Guilbert, Nathalie, Troadec, Marie-Bérengère
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833553/ https://www.ncbi.nlm.nih.gov/pubmed/35158909 http://dx.doi.org/10.3390/cancers14030643

Ejemplares similares

Cytogenetic and Genetic Abnormalities with Diagnostic Value in Myelodysplastic Syndromes (MDS): Focus on the Pre-Messenger RNA Splicing Process
por: Douet-Guilbert, Nathalie, et al.
Publicado: (2022)

TP53 in Myelodysplastic Syndromes
por: Jiang, Yan, et al.
Publicado: (2021)

Asian Population Is More Prone to Develop High-Risk Myelodysplastic Syndrome, Concordantly with Their Propensity to Exhibit High-Risk Cytogenetic Aberrations
por: Jiang, Yan, et al.
Publicado: (2021)

Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA
por: Sutherland, Leslie C., et al.
Publicado: (2017)

The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress
por: Lemaitre, Florence, et al.
Publicado: (2022)

Alternative splicing of BCL-x is controlled by RBM25 binding to a G-quadruplex in BCL-x pre-mRNA
por: Le Sénéchal, Ronan, et al.
Publicado: (2023)

ETV6-RUNX1 and RUNX1 directly regulate RAG1 expression: one more step in the understanding of childhood B-cell acute lymphoblastic leukemia leukemogenesis
por: Jakobczyk, Hélène, et al.
Publicado: (2021)

RBM20-Mediated Pre-mRNA Splicing Has Muscle-Specificity and Differential Hormonal Responses between Muscles and in Muscle Cell Cultures
por: Maimaiti, Rexiati, et al.
Publicado: (2021)

Angiotensin II Influences Pre-mRNA Splicing Regulation by Enhancing RBM20 Transcription Through Activation of the MAPK/ELK1 Signaling Pathway
por: Cai, Hanfang, et al.
Publicado: (2019)

Pre-mRNA Splicing in the Nuclear Landscape
por: Carrocci, Tucker J., et al.
Publicado: (2020)

Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis
por: Gabriel, Maude, et al.
Publicado: (2015)

Disassembly of interchromatin granule clusters alters the coordination of transcription and pre-mRNA splicing
por: Sacco-Bubulya, Paula, et al.
Publicado: (2002)

Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay
por: Sun, Yue, et al.
Publicado: (2017)

Alternative Splicing Regulator RBM20 and Cardiomyopathy
por: Watanabe, Takeshi, et al.
Publicado: (2018)

Human Cancer-Associated Mutations of SF3B1 Lead to a Splicing Modification of Its Own RNA
por: Bergot, Tiffany, et al.
Publicado: (2020)

G-Quadruplex Regulation of VEGFA mRNA Translation by RBM4
por: Niu, Kangkang, et al.
Publicado: (2022)

A Genetic Screen for Pre-mRNA Splicing Mutants of Arabidopsis thaliana Identifies Putative U1 snRNP Components RBM25 and PRP39a
por: Kanno, Tatsuo, et al.
Publicado: (2017)

Rbm20 regulates titin alternative splicing as a splicing repressor
por: Li, Shijun, et al.
Publicado: (2013)

RNA catalyzes nuclear pre-mRNA splicing
por: Fica, Sebastian M., et al.
Publicado: (2013)

Pre-mRNA splicing-associated diseases and therapies
por: Love, Sierra L., et al.
Publicado: (2023)

Prediction of alternative pre-mRNA splicing outcomes
por: Najjar, Rayan, et al.
Publicado: (2023)

Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors
Publicado: (1994)

Alternative Splicing of Cdh23 Exon 68 Is Regulated by RBM24, RBM38, and PTBP1
por: Li, Nana, et al.
Publicado: (2020)

Phylogenetic and Molecular Characterization of the Splicing Factor RBM4
por: Lu, Chia-Chen, et al.
Publicado: (2013)

Alu insertion variants alter mRNA splicing
por: Payer, Lindsay M, et al.
Publicado: (2019)

TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation
por: Lee, Kuo-Ming, et al.
Publicado: (2010)

MicroRNA-Biogenesis and Pre-mRNA Splicing Crosstalk
por: Shomron, Noam, et al.
Publicado: (2009)

Pre-mRNA Splicing Is a Determinant of Nucleosome Organization
por: Keren-Shaul, Hadas, et al.
Publicado: (2013)

Identification of Small Molecule Inhibitors of Pre-mRNA Splicing
por: Pawellek, Andrea, et al.
Publicado: (2014)

Quantification of pre-mRNA escape rate and synergy in splicing
por: Bonde, Marie Mi, et al.
Publicado: (2014)

Pre-mRNA splicing is a determinant of nucleosome organization
por: Keren-Shaul, Hadas, et al.
Publicado: (2013)

The Function of Pre-mRNA Alternative Splicing in Mammal Spermatogenesis
por: Song, Huibin, et al.
Publicado: (2020)

Alternative Splicing of Pre-mRNA in the Control of Immune Activity
por: Su, Zhongjing, et al.
Publicado: (2021)

The problem of selection bias in studies of pre-mRNA splicing
por: Dwyer, Zachary W., et al.
Publicado: (2023)

The role of alternative pre-mRNA splicing in cancer progression
por: Choi, Sunkyung, et al.
Publicado: (2023)

Differential Recruitment of Pre-mRNA Splicing Factors to Alternatively Spliced Transcripts In Vivo
por: Mabon, Stephen A, et al.
Publicado: (2005)

U1-independent pre-mRNA splicing contributes to the regulation of alternative splicing
por: Fukumura, Kazuhiro, et al.
Publicado: (2009)

Differential pre-mRNA Splicing Alters the Transcript Diversity of Helitrons Between the Maize Inbred Lines
por: Lynch, Brian T., et al.
Publicado: (2015)

U2AF1 Mutations Alter Sequence Specificity of pre-mRNA Binding and Splicing
por: Okeyo-Owuor, Theresa, et al.
Publicado: (2014)

Association of altered folylpolyglutamate synthetase pre-mRNA splicing with methotrexate unresponsiveness in early rheumatoid arthritis
por: Muller, Ittai B, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e6hukk5ja4hc8ph6i829gpfv5e